CHRNA3

CHRNA3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4ZK4
Identifiers
Aliases	CHRNA3, LNCR2, NACHRA3, PAOD2, cholinergic receptor nicotinic alpha 3 subunit
External IDs	MGI: 87887 HomoloGene: 591 GeneCards: CHRNA3
Gene ontology Molecular function • acetylcholine-activated cation-selective channel activity • ion channel activity • ligand-gated ion channel activity • extracellular ligand-gated ion channel activity • acetylcholine binding • acetylcholine receptor activity Cellular component • integral component of membrane • postsynaptic membrane • membrane • plasma membrane • synapse • cell junction • dendrite • acetylcholine-gated channel complex • postsynaptic density • neuronal cell body Biological process • locomotory behavior • regulation of smooth muscle contraction • regulation of membrane potential • regulation of acetylcholine secretion, neurotransmission • synaptic transmission, cholinergic • ion transport • cation transmembrane transport • nervous system development • behavioral response to nicotine • regulation of dendrite morphogenesis • synaptic transmission involved in micturition • excitatory postsynaptic potential • transport • activation of transmembrane receptor protein tyrosine kinase activity • signal transduction • ion transmembrane transport Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1136	110834
Ensembl	ENSG00000080644	ENSMUSG00000032303
UniProt	P32297	Q8R4G9
RefSeq (mRNA)	NM_000743 NM_001166694	NM_145129
RefSeq (protein)	NP_000734 NP_001160166	NP_660111.2 NP_660111
Location (UCSC)	Chr 15: 78.59 – 78.62 Mb	Chr 9: 55.01 – 55.03 Mb
PubMed search

4ZK4

1136

110834

ENSG00000080644

ENSMUSG00000032303

P32297

Q8R4G9

NM_000743
NM_001166694

NM_145129

NP_000734
NP_001160166

NP_660111.2
NP_660111

Neuronal acetylcholine receptor subunit alpha-3, also known as nAChRα3, is a protein that in humans is encoded by the CHRNA3 gene. The protein encoded by this gene is a subunit of certain nicotinic acetylcholine receptors (nAchR).

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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