CHD4

CHD4

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1MM2, 1MM3, 2EE1, 2L5U, 2L75, 4O9I, 2N5N

Identifiers

CHD4, CHD-4, Mi-2b, Mi2-BETA, chromodomain helicase DNA binding protein 4

External IDs

MGI: 1344380 HomoloGene: 68175 GeneCards: CHD4

Gene ontology
Molecular function	• RNA polymerase II distal enhancer sequence-specific DNA binding • DNA binding • nucleotide binding • helicase activity • microtubule binding • ATP-dependent DNA helicase activity • zinc ion binding • transcription factor binding • ATP-dependent helicase activity • metal ion binding • RNA polymerase II core promoter proximal region sequence-specific DNA binding • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • protein binding • RNA polymerase II repressing transcription factor binding • nucleic acid binding • nucleosomal DNA binding • hydrolase activity • ATP binding • histone deacetylase activity • histone deacetylase binding
Cellular component	• cytoplasm • NuRD complex • centrosome • membrane • nucleoplasm • protein complex • microtubule organizing center • protein-DNA complex • nuclear chromatin • cytoskeleton • nucleus
Biological process	• regulation of transcription, DNA-templated • regulation of transcription from RNA polymerase II promoter • negative regulation of transcription from RNA polymerase II promoter • transcription, DNA-templated • ATP-dependent chromatin remodeling • spindle assembly • terminal button organization • chromatin organization • histone deacetylation • DNA duplex unwinding • regulation of signal transduction by p53 class mediator • covalent chromatin modification
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE CHD4 201182 s at fs.png

PBB GE CHD4 201183 s at fs.png

PBB GE CHD4 201184 s at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


1108


107932


ENSG00000111642


ENSMUSG00000063870


Q14839


Q6PDQ2

RefSeq (mRNA)


NM_001273 NM_001297553


NM_145979 NM_001346610

RefSeq (protein)


NP_001264 NP_001284482


NP_666091.1 NP_001333539 NP_666091

Location (UCSC)

Chr 12: 6.57 – 6.61 Mb

Chr 6: 125.1 – 125.13 Mb

PubMed search

1MM2, 1MM3, 2EE1, 2L5U, 2L75, 4O9I, 2N5N

ENSG00000111642

ENSMUSG00000063870

NM_001273
NM_001297553

NM_145979
NM_001346610

NP_001264
NP_001284482

NP_666091.1
NP_001333539
NP_666091

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Wikipedia

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