CETN2

CETN2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1M39, 1ZMZ, 2A4J, 2GGM, 2K2I, 2OBH
Identifiers
Aliases	CETN2, CALT, CEN2, centrin 2
External IDs	MGI: 1347085 HomoloGene: 55798 GeneCards: CETN2
Gene ontology Molecular function • heterotrimeric G-protein binding • metal ion binding • calcium ion binding • G-protein beta/gamma-subunit complex binding • microtubule binding • protein binding Cellular component • photoreceptor connecting cilium • centriole • cytoplasm • nucleoplasm • ciliary basal body • cytosol • nucleus • XPC complex • centrosome • intracellular • cilium • cytoskeleton Biological process • nucleotide-excision repair, DNA damage recognition • cell cycle • spermatogenesis • cell division • G2/M transition of mitotic cell cycle • regulation of cytokinesis • centriole replication • cellular response to DNA damage stimulus • global genome nucleotide-excision repair • nucleotide-excision repair, preincision complex assembly • nucleotide-excision repair, DNA duplex unwinding • DNA repair • nucleotide-excision repair • ciliary basal body docking • mitotic cell cycle • regulation of G2/M transition of mitotic cell cycle Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1069	26370
Ensembl	ENSG00000147400	ENSMUSG00000031347
UniProt	P41208	Q9R1K9
RefSeq (mRNA)	NM_004344	NM_019405
RefSeq (protein)	NP_004335	NP_062278
Location (UCSC)	Chr X: 152.83 – 152.83 Mb	Chr X: 72.91 – 72.92 Mb
PubMed search

1M39, 1ZMZ, 2A4J, 2GGM, 2K2I, 2OBH

1069

26370

ENSG00000147400

ENSMUSG00000031347

P41208

Q9R1K9

NM_004344

NM_019405

NP_004335

NP_062278

Centrin-2 is a protein that in humans is encoded by the CETN2 gene. It belongs to the centrin family of proteins.

Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome.

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