CETN1

CETN1
Identifiers
Aliases	CETN1, CEN1, CETN, centrin 1
External IDs	MGI: 1347086 HomoloGene: 105668 GeneCards: CETN1
Gene location (Human) Chr. Chromosome 18 (human) Band No data available Start 580,357 bp End 582,114 bp
Gene location (Mouse) Chr. Chromosome 18 (mouse) Band No data available Start 9,615,524 bp End 9,619,478 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • microtubule binding • calcium ion binding • G-protein beta/gamma-subunit complex binding • heterotrimeric G-protein binding • protein binding • metal ion binding Cellular component • cytoplasm • microtubule organizing center • centrosome • spindle pole • cytoskeleton • photoreceptor connecting cilium • centriole Biological process • cell cycle • cellular response to heat • cell division Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	1068	26369
Ensembl	ENSG00000177143	ENSMUSG00000050996
UniProt	Q12798	P41209
RefSeq (mRNA)	NM_004066	NM_007593
RefSeq (protein)	NP_004057	NP_031619
Location (UCSC)	Chr 18: 0.58 – 0.58 Mb	Chr 18: 9.62 – 9.62 Mb
PubMed search

1068

26369

ENSG00000177143

ENSMUSG00000050996

Q12798

P41209

NM_004066

NM_007593

NP_004057

NP_031619

Centrin-1 is a protein that in humans is encoded by the CETN1 gene. It belongs to the centrin family of proteins.

The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This encoded protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle.

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Wikipedia