CEBPA

CEBPA

Identifiers

CEBPA, C/EBP-alpha, CEBP, CCAAT/enhancer binding protein alpha

External IDs

MGI: 99480 HomoloGene: 3211 GeneCards: CEBPA

Gene ontology
Molecular function	• RNA polymerase I regulatory region DNA binding • DNA binding • sequence-specific DNA binding • protein homodimerization activity • transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding • transcription factor activity, sequence-specific DNA binding • transcription coactivator activity • transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding • transcription factor binding • RNA polymerase II core promoter proximal region sequence-specific DNA binding • kinase binding • protein binding • transcription regulatory region DNA binding • transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
Cellular component	• transcription factor complex • RNA polymerase II transcription factor complex • nucleolus • nucleus • nucleoplasm • intracellular membrane-bounded organelle
Biological process	• Notch signaling pathway • transcription from RNA polymerase I promoter • myeloid cell differentiation • regulation of transcription, DNA-templated • cellular response to lithium ion • glucose homeostasis • negative regulation of cyclin-dependent protein serine/threonine kinase activity • lung development • cytokine-mediated signaling pathway • urea cycle • regulation of transcription from RNA polymerase II promoter • cellular response to organic cyclic compound • mitochondrion organization • embryonic placenta development • cholesterol metabolic process • negative regulation of cell cycle • negative regulation of transcription from RNA polymerase II promoter • cell maturation • generation of precursor metabolites and energy • transcription, DNA-templated • macrophage differentiation • multicellular organism development • positive regulation of transcription, DNA-templated • positive regulation of osteoblast differentiation • granulocyte differentiation • regulation of cell proliferation • brown fat cell differentiation • lipid homeostasis • white fat cell differentiation • inner ear development • liver development • viral process • negative regulation of transcription, DNA-templated • positive regulation of fat cell differentiation • positive regulation of transcription from RNA polymerase III promoter • fat cell differentiation • positive regulation of proteasomal ubiquitin-dependent protein catabolic process • positive regulation of transcription from RNA polymerase II promoter • negative regulation of cell proliferation • transcription from RNA polymerase II promoter • cellular response to tumor necrosis factor
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


1050


12606


ENSG00000245848


ENSMUSG00000034957


P49715


P53566

RefSeq (mRNA)


NM_004364 NM_001285829 NM_001287424 NM_001287435


NM_001287514 NM_001287515 NM_001287521 NM_001287523 NM_007678

RefSeq (protein)


NP_001272758 NP_001274353 NP_001274364 NP_004355

NP_001274443.1 NP_001274444.1 NP_001274450.1 NP_031704.2 NP_001274443
NP_001274444 NP_001274450 NP_001274452 NP_031704

Location (UCSC)

Chr 19: 33.3 – 33.3 Mb

Chr 7: 35.12 – 35.12 Mb

PubMed search

ENSG00000245848

ENSMUSG00000034957

NM_004364
NM_001285829
NM_001287424
NM_001287435

NM_001287514
NM_001287515
NM_001287521
NM_001287523
NM_007678

NP_001272758
NP_001274353
NP_001274364
NP_004355

NP_001274444
NP_001274450
NP_001274452
NP_031704

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Wikipedia

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