CEACAM1

CEACAM1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2GK2, 4QXW, 5DZL, 4WHD
Identifiers
Aliases	CEACAM1, BGP, BGP1, BGPI, carcinoembryonic antigen related cell adhesion molecule 1
External IDs	MGI: 1347245 HomoloGene: 128630 GeneCards: CEACAM1
Gene ontology Molecular function • protein binding • kinase binding • protein homodimerization activity • protein phosphatase binding • protein tyrosine kinase binding • filamin binding • bile acid transmembrane transporter activity • protein dimerization activity • actin binding Cellular component • extracellular region • integral component of plasma membrane • extracellular exosome • T cell receptor complex • cell-cell junction • membrane • cell surface • integral component of membrane • plasma membrane • adherens junction • basal plasma membrane • apical plasma membrane • lateral plasma membrane • cell junction • transport vesicle membrane • cytoplasmic vesicle • microvillus membrane • specific granule membrane • cell projection • tertiary granule membrane Biological process • integrin-mediated signaling pathway • cell migration • angiogenesis • leukocyte migration • insulin catabolic process • positive regulation of vasculogenesis • cellular response to insulin stimulus • negative regulation of cytotoxic T cell degranulation • regulation of ERK1 and ERK2 cascade • regulation of homophilic cell adhesion • negative regulation of vascular permeability • regulation of endothelial cell migration • negative regulation of interleukin-1 production • homophilic cell adhesion via plasma membrane adhesion molecules • granulocyte colony-stimulating factor signaling pathway • wound healing, spreading of cells • negative regulation of hepatocyte proliferation • negative regulation of granulocyte differentiation • negative regulation of platelet aggregation • blood vessel development • negative regulation of lipid biosynthetic process • bile acid and bile salt transport • regulation of blood vessel remodeling • negative regulation of T cell receptor signaling pathway • negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target • regulation of cell growth • insulin receptor internalization • negative regulation of T cell mediated cytotoxicity • regulation of sprouting angiogenesis • negative regulation of protein kinase activity • negative regulation of fatty acid biosynthetic process • regulation of cell migration • regulation of phosphatidylinositol 3-kinase signaling • common myeloid progenitor cell proliferation • regulation of epidermal growth factor receptor signaling pathway • regulation of endothelial cell differentiation • cell adhesion • neutrophil degranulation • cell-cell adhesion via plasma-membrane adhesion molecules Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	634	26365
Ensembl	ENSG00000079385	ENSMUSG00000074272
UniProt	P13688 Q3KRG8	P31809
RefSeq (mRNA)	NM_001024912 NM_001184813 NM_001184815 NM_001184816 NM_001205344 NM_001712	NM_001039185 NM_001039186 NM_001039187 NM_011926
RefSeq (protein)	NP_001020083 NP_001171742 NP_001171744 NP_001171745 NP_001192273 NP_001703 NP_001020083.1	NP_001034274.1 NP_001034275.1 NP_001034274 NP_001034275 NP_001034276 NP_036056
Location (UCSC)	Chr 19: 42.51 – 42.56 Mb	Chr 7: 25.46 – 25.48 Mb
PubMed search

2GK2, 4QXW, 5DZL, 4WHD

634

26365

ENSG00000079385

ENSMUSG00000074272

P13688
Q3KRG8

P31809

NM_001712

NM_001039185
NM_001039186
NM_001039187
NM_011926

NP_001703
NP_001020083.1

NP_036056

Carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (CEACAM1) also known as CD66a (Cluster of Differentiation 66a), is a human glycoprotein, encoded by a gene.

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