CDH2

CDH2

Protein CDH2 PDB 1ncg.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1NCG, 1NCH, 1NCI, 1NCJ, 1OP4, 2QVI, 3Q2W, 4NUM, 4NUP, 4NUQ

Identifiers

CDH2, CD325, CDHN, CDw325, NCAD, cadherin 2

External IDs

MGI: 88355 HomoloGene: 20424 GeneCards: CDH2

Gene ontology
Molecular function	• calcium ion binding • gamma-catenin binding • metal ion binding • protein binding • enzyme binding • protein phosphatase binding • alpha-catenin binding • beta-catenin binding • protein kinase binding
Cellular component	• cytoplasm • integral component of membrane • membrane • intercalated disc • cell-cell junction • focal adhesion • plasma membrane raft • adherens junction • plasma membrane • synapse • basolateral plasma membrane • apical plasma membrane • cortical actin cytoskeleton • catenin complex • fascia adherens • extracellular exosome • lamellipodium • cell-cell adherens junction • postsynaptic density • sarcolemma • endoplasmic reticulum lumen • cell surface • cell junction
Biological process	• calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules • heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules • blood vessel morphogenesis • homeostasis of number of cells • positive regulation of muscle cell differentiation • regulation of postsynaptic density protein 95 clustering • glial cell differentiation • neuroepithelial cell differentiation • cell-cell adhesion mediated by cadherin • radial glial cell differentiation • neuronal stem cell population maintenance • regulation of oligodendrocyte progenitor proliferation • telencephalon development • neuroligin clustering involved in postsynaptic membrane assembly • positive regulation of synaptic vesicle clustering • cell adhesion • regulation of signal transduction • cerebral cortex development • striated muscle cell differentiation • adherens junction organization • cell migration • negative regulation of canonical Wnt signaling pathway • positive regulation of MAPK cascade • establishment of protein localization to plasma membrane • homophilic cell adhesion via plasma membrane adhesion molecules • brain morphogenesis • post-translational protein modification • cellular protein metabolic process
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE CDH2 203441 s at fs.png

PBB GE CDH2 203440 at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


1000


12558


ENSG00000170558


ENSMUSG00000024304


P19022


P15116

RefSeq (mRNA)


NM_001308176 NM_001792


NM_007664

RefSeq (protein)


NP_001295105 NP_001783 NP_001783.2


NP_031690.3 NP_031690

Location (UCSC)

Chr 18: 27.95 – 28.18 Mb

Chr 18: 16.59 – 16.81 Mb

PubMed search

1NCG, 1NCH, 1NCI, 1NCJ, 1OP4, 2QVI, 3Q2W, 4NUM, 4NUP, 4NUQ

ENSG00000170558

ENSMUSG00000024304

NM_001308176
NM_001792

NP_001295105
NP_001783
NP_001783.2

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Wikipedia

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