CDH1 (gene)

CDH1

PBB Protein CDH1 image.jpg

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE

Identifiers

CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO, cadherin 1

External IDs

MGI: 88354 HomoloGene: 20917 GeneCards: CDH1

Genetically Related Diseases

colorectal cancer

Gene ontology
Molecular function	• calcium ion binding • protein binding • ankyrin binding • gamma-catenin binding • beta-catenin binding • GTPase activating protein binding • glycoprotein binding • metal ion binding • cell adhesion molecule binding • cadherin binding
Cellular component	• cell-cell adherens junction • apical junction complex • trans-Golgi network • extracellular region • perinuclear region of cytoplasm • cortical actin cytoskeleton • Golgi apparatus • lamellipodium • cytoplasmic side of plasma membrane • endosome • lateral plasma membrane • catenin complex • actin cytoskeleton • flotillin complex • membrane • extracellular exosome • integral component of membrane • cell junction • cytoplasm • plasma membrane
Biological process	• negative regulation of cell-cell adhesion • positive regulation of transcription, DNA-templated • cellular response to lithium ion • cell adhesion • extracellular matrix organization • response to drug • protein localization to plasma membrane • cellular response to indole-3-methanol • extracellular matrix disassembly • synapse assembly • positive regulation of transcription factor import into nucleus • pituitary gland development • establishment of protein localization to plasma membrane • response to toxic substance • response to organic substance • single organismal cell-cell adhesion • neuron projection development • adherens junction organization • homophilic cell adhesion via plasma membrane adhesion molecules • entry of bacterium into host cell
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE CDH1 201131 s at fs.png

PBB GE CDH1 201130 s at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


999


12550


ENSG00000039068


ENSMUSG00000000303


P12830


P09803

RefSeq (mRNA)


NM_004360 NM_001317184 NM_001317185 NM_001317186


NM_009864

RefSeq (protein)


NP_001304113 NP_001304114 NP_001304115 NP_004351


NP_033994.1 NP_033994

Location (UCSC)

Chr 16: 68.74 – 68.84 Mb

Chr 8: 106.6 – 106.67 Mb

PubMed search

1O6S, 2O72, 2OMT, 2OMU, 2OMV, 2OMX, 2OMY, 2OMZ, 3FF7, 3FF8, 3L6X, 3L6Y, 4ZT1, 4ZTE

ENSG00000039068

ENSMUSG00000000303

NM_004360
NM_001317184
NM_001317185
NM_001317186

...
Wikipedia

...