CD81

CD81
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1G8Q, 1IV5, 3X0E, 5DFW, 5DFV
Identifiers
Aliases	CD81, CVID6, S5.7, TAPA1, TSPAN28, CD81 molecule
External IDs	MGI: 1096398 HomoloGene: 20915 GeneCards: CD81
Gene ontology Molecular function • protein binding • MHC class II protein complex binding • transferrin receptor binding • virus receptor activity Cellular component • integral component of membrane • vesicle • membrane • focal adhesion • plasma membrane • integral component of plasma membrane • immunological synapse • extracellular exosome • basolateral plasma membrane Biological process • positive regulation of 1-phosphatidylinositol 4-kinase activity • protein localization • regulation of protein stability • receptor internalization • cellular response to low-density lipoprotein particle stimulus • regulation of cell motility • receptor-mediated virion attachment to host cell • protein localization to lysosome • cell surface receptor signaling pathway • activation of MAPK activity • positive regulation of B cell proliferation • positive regulation of cell proliferation • regulation of immune response • positive regulation of peptidyl-tyrosine phosphorylation • viral entry into host cell • positive regulation of protein catabolic process in the vacuole • cell proliferation • viral process • positive regulation of transcription from RNA polymerase II promoter • regulation of complement activation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	975	12520
Ensembl	ENSG00000110651	ENSMUSG00000037706
UniProt	P60033	P35762
RefSeq (mRNA)	NM_001297649 NM_004356	NM_133655
RefSeq (protein)	NP_001284578 NP_004347	NP_598416.1 NP_598416
Location (UCSC)	Chr 11: 2.38 – 2.4 Mb	Chr 7: 143.05 – 143.07 Mb
PubMed search

1G8Q, 1IV5, 3X0E, 5DFW, 5DFV

975

12520

ENSG00000110651

ENSMUSG00000037706

P60033

P35762

NM_001297649
NM_004356

NM_133655

NP_001284578
NP_004347

NP_598416.1
NP_598416

CD81 molecule, also known as CD81 (Cluster of Differentiation 81), is a protein which in humans is encoded by the CD81 gene. It is also known as 26 kDa cell surface protein, TAPA-1 (Target of the Antiproliferative Antibody 1), and Tetraspanin-28 (Tspan-28).

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Wikipedia