CD79A

CD79A
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1CV9
Identifiers
Aliases	CD79A, IGA, MB-1, CD79a molecule
External IDs	MGI: 101774 HomoloGene: 31053 GeneCards: CD79A
Gene ontology Molecular function • protein binding • transmembrane signaling receptor activity • protein homodimerization activity Cellular component • integral component of membrane • multivesicular body • membrane raft • plasma membrane • membrane • external side of plasma membrane • cytoplasm • B cell receptor complex • integral component of plasma membrane Biological process • B cell activation • B cell proliferation • cell surface receptor signaling pathway • adaptive immune response • immune system process • B cell differentiation • B cell receptor signaling pathway • protein homotetramerization Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	973	12518
Ensembl	ENSG00000105369	ENSMUSG00000003379
UniProt	P11912	P11911
RefSeq (mRNA)	NM_021601 NM_001783	NM_007655
RefSeq (protein)	NP_001774 NP_067612	NP_031681.2 NP_031681
Location (UCSC)	Chr 19: 41.88 – 41.88 Mb	Chr 7: 24.9 – 24.9 Mb
PubMed search

1CV9

973

12518

ENSG00000105369

ENSMUSG00000003379

P11912

P11911

NM_021601
NM_001783

NM_007655

NP_001774
NP_067612

NP_031681.2
NP_031681

Cluster of differentiation CD79A also known as B-cell antigen receptor complex-associated protein alpha chain and MB-1 membrane glycoprotein, is a protein that in humans is encoded by the CD79A gene.

The CD79a protein together with the related CD79b protein, forms a dimer associated with membrane-bound immunoglobulin in B-cells, thus forming the B-cell antigen receptor (BCR). This occurs in a similar manner to the association of CD3 with the T-cell receptor, and enables the cell to respond to the presence of antigens on its surface.

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Wikipedia