CD69

CD69
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1E87, 1E8I, 1FM5, 3CCK, 3HUP
Identifiers
Aliases	CD69, AIM, BL-AC/P26, CLEC2C, EA1, GP32/28, MLR-3, CD69 molecule
External IDs	MGI: 88343 HomoloGene: 128584 GeneCards: CD69
Gene ontology Molecular function • calcium ion binding • protein binding • transmembrane signaling receptor activity • carbohydrate binding • protein homodimerization activity Cellular component • integral component of membrane • integral component of plasma membrane • membrane • external side of plasma membrane • protein complex Biological process • cellular response to drug • signal transduction Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	969	12515
Ensembl	ENSG00000110848	ENSMUSG00000030156
UniProt	Q07108	P37217
RefSeq (mRNA)	NM_001781	NM_001033122
RefSeq (protein)	NP_001772	NP_001028294.1 NP_001028294
Location (UCSC)	Chr 12: 9.75 – 9.76 Mb	Chr 6: 129.27 – 129.28 Mb
PubMed search

1E87, 1E8I, 1FM5, 3CCK, 3HUP

969

12515

ENSG00000110848

ENSMUSG00000030156

Q07108

P37217

NM_001781

NM_001033122

NP_001772

NP_001028294.1
NP_001028294

CD69 (Cluster of Differentiation 69) is a human transmembrane C-Type lectin protein encoded by the CD69 gene.

The activation of T lymphocytes and Natural Killer (NK) Cells, both in vivo and in vitro, induces expression of CD69. This molecule, which appears to be the earliest inducible cell surface glycoprotein acquired during lymphoid activation, is involved in lymphocyte proliferation and functions as a signal-transmitting receptor in lymphocytes, including natural killer (NK) cells, and platelets (Cambiaggi et al., 1992) [supplied by OMIM].

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Wikipedia