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CD66d

CEACAM3
Identifiers
Aliases CEACAM3, CD66D, CEA, CGM1, W264, W282, carcinoembryonic antigen related cell adhesion molecule 3
External IDs HomoloGene: 130497 GeneCards: CEACAM3
RNA expression pattern
PBB GE CEACAM3 208052 x at fs.png

PBB GE CEACAM3 210789 x at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001277163
NM_001815

n/a

RefSeq (protein)

NP_001264092
NP_001806

n/a

Location (UCSC) Chr 19: 41.8 – 41.81 Mb n/a
PubMed search n/a

NM_001277163
NM_001815

n/a

NP_001264092
NP_001806

n/a

Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) also known as CD66d (Cluster of Differentiation 66d), is a human gene.

This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

CEACAM3 is expressed exclusively on granulocytes and used as granulocyte marker.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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