CD44

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1POZ, 1UUH, 2I83, 4PZ3, 4PZ4

Identifiers

Aliases

CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CD44 molecule (Indian blood group)

External IDs

OMIM: 107269 MGI: 88338 HomoloGene: 508 GeneCards: CD44

Gene ontology
Molecular function	• collagen binding • protein binding • hyaluronic acid binding • cytokine receptor activity
Cellular component	• integral component of membrane • Golgi apparatus • macrophage migration inhibitory factor receptor complex • membrane • focal adhesion • plasma membrane • integral component of plasma membrane • cell surface • extracellular exosome • cytosol • secretory granule membrane
Biological process	• single organismal cell-cell adhesion • negative regulation of cysteine-type endopeptidase activity involved in apoptotic process • monocyte aggregation • positive regulation of heterotypic cell-cell adhesion • hyaluronan catabolic process • negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator • interferon-gamma-mediated signaling pathway • extracellular matrix disassembly • extracellular matrix organization • negative regulation of apoptotic process • cellular response to fibroblast growth factor stimulus • positive regulation of peptidyl-serine phosphorylation • cartilage development • cell adhesion • negative regulation of DNA damage response, signal transduction by p53 class mediator • positive regulation of ERK1 and ERK2 cascade • positive regulation of peptidyl-tyrosine phosphorylation • cell-matrix adhesion • positive regulation of monocyte aggregation • leukocyte migration • neutrophil degranulation • positive regulation of kinase activity
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


960


12505

Ensembl


ENSG00000026508


ENSMUSG00000005087

UniProt


P16070


P15379

RefSeq (mRNA)

NM_000610 NM_001001389 NM_001001390 NM_001001391 NM_001001392
NM_001202555 NM_001202556 NM_001202557

NM_001039150 NM_001039151 NM_001177785 NM_001177786 NM_001177787
NM_009851

RefSeq (protein)

NP_000601 NP_001001389 NP_001001390 NP_001001391 NP_001001392
NP_001189484 NP_001189485 NP_001189486

NP_001034240.1 NP_001171256.1 NP_001171257.1 NP_001171258.1 NP_033981.2
NP_001034239 NP_001034240 NP_001171256 NP_001171257 NP_001171258 NP_033981

Location (UCSC)

Chr 11: 35.14 – 35.23 Mb

Chr 2: 102.81 – 102.9 Mb

PubMed search

1POZ, 1UUH, 2I83, 4PZ3, 4PZ4

NM_001202555
NM_001202556
NM_001202557

NM_009851

NP_001189484
NP_001189485
NP_001189486

NP_001034239
NP_001034240
NP_001171256
NP_001171257
NP_001171258
NP_033981

...
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