CD3G

CD3G
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1SY6
Identifiers
Aliases	CD3G, CD3-GAMMA, IMD17, T3G, CD3g molecule
External IDs	MGI: 88333 HomoloGene: 55 GeneCards: CD3G
Gene ontology Molecular function • receptor signaling complex scaffold activity • T cell receptor binding • transmembrane signaling receptor activity • protein heterodimerization activity Cellular component • integral component of membrane • plasma membrane • alpha-beta T cell receptor complex • integral component of plasma membrane • T cell receptor complex • membrane • clathrin-coated vesicle membrane Biological process • protein transport • establishment or maintenance of cell polarity • T cell costimulation • cell surface receptor signaling pathway • T cell receptor signaling pathway • regulation of lymphocyte apoptotic process • T cell activation • Fc-gamma receptor signaling pathway involved in phagocytosis • protein complex assembly • regulation of immune response • membrane organization Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	917	12502
Ensembl	ENSG00000160654	ENSMUSG00000002033
UniProt	P09693	P11942
RefSeq (mRNA)	NM_000073	NM_009850
RefSeq (protein)	NP_000064	NP_033980.1 NP_033980
Location (UCSC)	Chr 11: 118.34 – 118.36 Mb	Chr 9: 44.97 – 44.98 Mb
PubMed search

1SY6

917

12502

ENSG00000160654

ENSMUSG00000002033

P09693

P11942

NM_000073

NM_009850

NP_000064

NP_033980.1
NP_033980

T-cell surface glycoprotein CD3 gamma chain is a protein that in humans is encoded by the CD3G gene.

T cell antigen receptor (TCR) is associated on the T cell surface with a complex of protein called CD3. CD3G (gamma chain) is one of the four peptides (gamma, delta, epsilon and zeta) that form CD3. Defects in CD3G are associated with T cell immunodeficiency.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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