CD3EAP

CD3EAP
Identifiers
Aliases	CD3EAP, ASE-1, ASE1, CAST, PAF49, CD3e molecule associated protein
External IDs	MGI: 1917583 HomoloGene: 17107 GeneCards: CD3EAP
Gene location (Human) Chr. Chromosome 19 (human) Band 19q13.32 Start 45,406,209 bp End 45,410,766 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7|7 A3 Start 19,356,014 bp End 19,359,483 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • DNA-directed 5'-3' RNA polymerase activity • RNA binding Cellular component • DNA-directed RNA polymerase I complex • RNA polymerase I transcription factor complex • mitochondrion • nucleus • nucleoplasm • chromosome • fibrillar center • nucleolus • cytosol Biological process • transcription initiation from RNA polymerase I promoter • termination of RNA polymerase I transcription • positive regulation of gene expression, epigenetic • rRNA transcription • transcription elongation from RNA polymerase I promoter • transmembrane receptor protein tyrosine kinase signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	10849	70333
Ensembl	ENSG00000117877	ENSMUSG00000047649
UniProt	O15446	Q76KJ5
RefSeq (mRNA)	NM_012099 NM_001297590	NM_145822
RefSeq (protein)	NP_001284519 NP_036231	NP_665821
Location (UCSC)	Chr 19: 45.41 – 45.41 Mb	Chr 19: 19.36 – 19.36 Mb
PubMed search

10849

70333

ENSG00000117877

ENSMUSG00000047649

O15446

Q76KJ5

NM_012099
NM_001297590

NM_145822

NP_001284519
NP_036231

NP_665821

DNA-directed RNA polymerase I subunit RPA34 is an enzyme that in humans is encoded by the CD3EAP gene.

CD3EAP has been shown to interact with T-cell surface glycoprotein CD3 epsilon chain,POLR1E and POLR1C.

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Wikipedia