CD36

Identifiers

CD36, BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3, CD36 molecule

External IDs

OMIM: 173510 MGI: 107899 HomoloGene: 73871 GeneCards: CD36

Gene ontology
Molecular function	• protein binding • low-density lipoprotein receptor activity • transforming growth factor beta binding • high-density lipoprotein particle binding • lipoprotein particle binding • thrombospondin receptor activity • lipid binding • low-density lipoprotein particle binding • lipoteichoic acid receptor activity
Cellular component	• Golgi apparatus • apical plasma membrane • phagocytic vesicle • apical part of cell • brush border membrane • endocytic vesicle membrane • integral component of plasma membrane • membrane • external side of plasma membrane • integral component of membrane • platelet alpha granule membrane • membrane raft • cell surface • plasma membrane • extracellular space • specific granule membrane
Biological process	• low-density lipoprotein particle mediated signaling • apoptotic cell clearance • positive regulation of MAPK cascade • response to lipid • nitric oxide mediated signal transduction • intestinal absorption • positive regulation of blood microparticle formation • positive regulation of blood coagulation • negative regulation of growth of symbiont in host • plasma lipoprotein particle clearance • negative regulation of transcription factor import into nucleus • sensory perception of taste • blood coagulation • cellular response to hydroperoxide • positive regulation of ERK1 and ERK2 cascade • receptor internalization • cellular response to bacterial lipopeptide • amyloid fibril formation • cellular response to lipopolysaccharide • cell surface receptor signaling pathway • antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent • cholesterol transport • platelet degranulation • cholesterol import • cellular response to diacyl bacterial lipopeptide • negative regulation of transcription from RNA polymerase II promoter • transport • toll-like receptor TLR6:TLR2 signaling pathway • interleukin-1 beta secretion • phagocytosis, recognition • cellular response to low-density lipoprotein particle stimulus • positive regulation of macrophage cytokine production • immune response • response to linoleic acid • negative regulation of gene expression • positive regulation of reactive oxygen species metabolic process • lipoprotein transport • positive regulation of cell-matrix adhesion • positive regulation of interleukin-12 production • triglyceride transport • long-chain fatty acid import • MyD88-dependent toll-like receptor signaling pathway • response to fatty acid • regulation of removal of superoxide radicals • cellular response to lipoteichoic acid • positive regulation of cholesterol storage • intestinal cholesterol absorption • positive regulation of tumor necrosis factor production • receptor-mediated endocytosis • regulation of energy homeostasis • lipid metabolic process • cGMP-mediated signaling • positive regulation of phagocytosis, engulfment • defense response to Gram-positive bacterium • positive regulation of cytosolic calcium ion concentration • positive regulation of interleukin-6 production • positive regulation of peptidyl-tyrosine phosphorylation • positive regulation of I-kappaB kinase/NF-kappaB signaling • response to stilbenoid • positive regulation of NLRP3 inflammasome complex assembly • low-density lipoprotein particle clearance • lipid storage • positive regulation of macrophage derived foam cell differentiation • cell adhesion • toll-like receptor signaling pathway • neutrophil degranulation
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


948


12491

Ensembl


ENSG00000135218


ENSMUSG00000002944

UniProt


P16671


Q08857

RefSeq (mRNA)

NM_000072 NM_001001547 NM_001001548 NM_001127443 NM_001127444
NM_001289908 NM_001289909 NM_001289911


NM_001159555 NM_001159556 NM_001159557 NM_001159558 NM_007643

RefSeq (protein)

NP_000063 NP_001001547 NP_001001548 NP_001120915 NP_001120916
NP_001276837 NP_001276838 NP_001276840

NP_001153027.1 NP_001153028.1 NP_001153029.1 NP_001153030.1 NP_031669.3
NP_001153027 NP_001153028 NP_001153029 NP_001153030 NP_031669

Location (UCSC)

Chr 7: 80.37 – 80.68 Mb

Chr 5: 17.78 – 17.89 Mb

PubMed search

CD36 family

Structure of Limp-II. PDB entry 4f7b

Identifiers

Symbol

CD36

Available protein structures:
Pfam	structures
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Available protein structures:
Pfam	structures
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

NM_001289908
NM_001289909
NM_001289911

NM_001159555
NM_001159556
NM_001159557
NM_001159558
NM_007643

NP_001276837
NP_001276838
NP_001276840

NP_001153027
NP_001153028
NP_001153029
NP_001153030
NP_031669

...
Wikipedia