CD22

CD22
Identifiers
Aliases	CD22, SIGLEC-2, SIGLEC2, CD22 molecule
External IDs	OMIM: 107266 MGI: 88322 HomoloGene: 31052 GeneCards: CD22
Gene ontology Molecular function • protein binding • carbohydrate binding Cellular component • integral component of membrane • plasma membrane • extracellular exosome • membrane Biological process • cell adhesion Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	933	12483
Ensembl	ENSG00000012124	ENSMUSG00000030577
UniProt	P20273	P35329
RefSeq (mRNA)	NM_024916 NM_001185099 NM_001185100 NM_001185101 NM_001278417 NM_001771	NM_001043317 NM_009845
RefSeq (protein)	NP_001172028 NP_001172029 NP_001172030 NP_001265346 NP_001762	NP_001036782.1 NP_033975.3 NP_001036782 NP_033975
Location (UCSC)	Chr 19: 35.32 – 35.35 Mb	Chr 7: 30.87 – 30.88 Mb
PubMed search

933

12483

ENSG00000012124

ENSMUSG00000030577

P20273

P35329

NM_001771

NM_001043317
NM_009845

NP_001172028
NP_001172029
NP_001172030
NP_001265346
NP_001762

NP_001036782.1
NP_033975.3
NP_001036782
NP_033975

CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. Generally speaking, CD22 is a regulatory molecule that prevents the overactivation of the immune system and the development of autoimmune diseases.

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Wikipedia