CCR7

CCR7

Identifiers

CCR7, BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1, C-C motif chemokine receptor 7

External IDs

MGI: 103011 HomoloGene: 1387 GeneCards: CCR7

Gene ontology
Molecular function	• C-C motif chemokine 19 receptor activity • C-C motif chemokine 21 receptor activity • G-protein coupled receptor activity • chemokine (C-C motif) ligand 19 binding • chemokine (C-C motif) ligand 21 binding • signal transducer activity • chemokine receptor activity • C-C chemokine receptor activity
Cellular component	• integral component of membrane • membrane • plasma membrane • intracellular • cell surface • external side of plasma membrane
Biological process	• regulation of interleukin-1 beta secretion • G-protein coupled receptor signaling pathway • release of sequestered calcium ion into cytosol • positive regulation of protein kinase B signaling • positive regulation of cell motility • positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation • positive regulation of actin filament polymerization • lymphocyte migration into lymph node • homeostasis of number of cells • positive regulation of interleukin-12 production • positive regulation of hypersensitivity • activation of GTPase activity • ruffle organization • positive regulation of cell-matrix adhesion • positive regulation of cytosolic calcium ion concentration • positive regulation of T cell receptor signaling pathway • regulation of interferon-gamma production • response to nitric oxide • regulation of dendritic cell dendrite assembly • positive regulation of JNK cascade • myeloid dendritic cell chemotaxis • dendritic cell chemotaxis • cellular response to cytokine stimulus • negative thymic T cell selection • positive regulation of phosphatidylinositol 3-kinase activity • chemotaxis • positive regulation of immunological synapse formation • response to prostaglandin E • interleukin-12 secretion • response to lipopolysaccharide • positive regulation of dendritic cell antigen processing and presentation • positive regulation of pseudopodium assembly • positive regulation of humoral immune response • immune response • establishment of T cell polarity • positive regulation of ERK1 and ERK2 cascade • positive regulation of neutrophil chemotaxis • positive regulation of I-kappaB kinase/NF-kappaB signaling • negative regulation of leukocyte apoptotic process • positive regulation of T cell costimulation • inflammatory response • mature conventional dendritic cell differentiation • positive regulation of filopodium assembly • positive regulation of dendritic cell chemotaxis • signal transduction • positive regulation of cell adhesion • positive regulation of protein kinase activity • chemokine-mediated signaling pathway • chemokine (C-C motif) ligand 19 signaling pathway • chemokine (C-C motif) ligand 21 signaling pathway
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE CCR7 206337 at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


1236


12775


ENSG00000126353


ENSMUSG00000037944


P32248


P47774

RefSeq (mRNA)


NM_001838 NM_001301714 NM_001301716 NM_001301717 NM_001301718


NM_001301713 NM_007719

RefSeq (protein)


NP_001288643 NP_001288645 NP_001288646 NP_001288647 NP_001829


NP_001288642.1 NP_031745.2 NP_001288642 NP_031745

Location (UCSC)

Chr 17: 40.55 – 40.57 Mb

Chr 11: 99.14 – 99.16 Mb

PubMed search

ENSG00000126353

ENSMUSG00000037944

NM_001838
NM_001301714
NM_001301716
NM_001301717
NM_001301718

NM_001301713
NM_007719

NP_001288643
NP_001288645
NP_001288646
NP_001288647
NP_001829

NP_001288642.1
NP_031745.2
NP_001288642
NP_031745

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Wikipedia

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