César Milstein | |
---|---|
Born |
Bahía Blanca, Argentina |
8 October 1927
Died | 24 March 2002 Cambridge, England |
(aged 74)
Nationality | Argentinian, naturalised as British |
Fields | Biochemistry |
Alma mater | |
Doctoral advisor | Stoppani |
Known for | Receiving Nobel Prize "for theories concerning the specificity in development and control of the immune system and the discovery of the principle for production of monoclonal antibodies" |
Notable awards |
|
Spouse | Celia Prilleltensky (m. 1953) |
César Milstein, CH, FRS (8 October 1927 – 24 March 2002) was an Argentinian biochemist in the field of antibody research. Milstein shared the Nobel Prize in Physiology or Medicine in 1984 with Niels Kaj Jerne and Georges J. F. Köhler.
Milstein was born in Bahía Blanca, Argentina. His parents were Máxima (Vapniarsky) and Lázaro Milstein, a Jewish Ukrainian immigrant. He graduated from the University of Buenos Aires and obtained a PhD under Professor Stoppani (Professor of Biochemistry). In 1956 he received an award from the Sociedad Bioquímica Argentina for his work on kinetic studies with the enzyme aldehyde dehydrogenase. In 1958, funded by the British Council, he joined the Biochemistry Department at the University of Cambridge at Darwin College to work for a PhD under Malcolm Dixon on the mechanism of metal activation of the enzyme phosphoglucomutase. During this work he collaborated with Frederick Sanger whose group he joined with a short-term Medical Research Council appointment.