Butyrylcholinesterase

BCHE
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1P0P, 4AXB, 4B0P, 2XQG, 1XLV, 2WIK, 2WIL, 1P0Q, 1XLU, 4BDS, 2XQF, 2PM8, 2XQK, 4AQD, 4BBZ, 2WID, 2XMB, 1XLW, 2XMC, 4TPK, 2XMG, 2XMD, 3DKK, 3O9M, 2WSL, 2WIJ, 1P0I, 2WIG, 2XQJ, 3DJY, 1P0M, 4B0O, 2XQI, 2Y1K, 4XII, 2WIF, 2J4C
Identifiers
Aliases	BCHE, CHE1, CHE2, E1, butyrylcholinesterase
External IDs	OMIM: 177400 MGI: 894278 HomoloGene: 20065 GeneCards: BCHE
Genetically Related Diseases
cardiovascular system disease
Targeted by Drug
bambuterol, physostigmine, pyridostigmine, rivastigmine, tacrine
Gene ontology Molecular function • carboxylic ester hydrolase activity • beta-amyloid binding • cholinesterase activity • choline binding • catalytic activity • identical protein binding • acetylcholinesterase activity • enzyme binding • hydrolase activity • hydrolase activity, acting on ester bonds Cellular component • endoplasmic reticulum lumen • blood microparticle • membrane • extracellular region • endoplasmic reticulum • nuclear envelope lumen • extracellular space Biological process • choline metabolic process • response to nutrient • neuroblast differentiation • response to glucocorticoid • negative regulation of synaptic transmission • learning • cocaine metabolic process • response to alkaloid • response to folic acid • response to drug • negative regulation of cell proliferation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	590	12038
Ensembl	ENSG00000114200	ENSMUSG00000027792
UniProt	P06276	Q03311
RefSeq (mRNA)	NM_000055	NM_009738
RefSeq (protein)	NP_000046	NP_033868.3 NP_033868
Location (UCSC)	Chr 3: 165.77 – 165.84 Mb	Chr 3: 73.64 – 73.71 Mb
PubMed search

1P0P, 4AXB, 4B0P, 2XQG, 1XLV, 2WIK, 2WIL, 1P0Q, 1XLU, 4BDS, 2XQF, 2PM8, 2XQK, 4AQD, 4BBZ, 2WID, 2XMB, 1XLW, 2XMC, 4TPK, 2XMG, 2XMD, 3DKK, 3O9M, 2WSL, 2WIJ, 1P0I, 2WIG, 2XQJ, 3DJY, 1P0M, 4B0O, 2XQI, 2Y1K, 4XII, 2WIF, 2J4C

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