Brain-derived neurotrophic factor

BDNF

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1BND, 1B8M

Identifiers

BDNF, brain-derived neurotrophic factor, ANON2, BULN2, Brain-derived neurotrophic factor, brain derived neurotrophic factor

External IDs

Genetically Related Diseases

Gene ontology
Molecular function	• receptor binding • neurotrophin TRKB receptor binding • growth factor activity
Cellular component	• cytoplasm • perinuclear region of cytoplasm • extracellular region • mitochondrion • nuclear speck • cytoplasmic vesicle
Biological process	• brain-derived neurotrophic factor receptor signaling pathway • negative regulation of neuron apoptotic process • synapse assembly • cell-cell signaling • positive regulation of brain-derived neurotrophic factor receptor signaling pathway • collateral sprouting • positive regulation of synapse assembly • positive regulation of collateral sprouting • nervous system development • axon guidance • negative regulation of myotube differentiation • positive regulation of receptor binding • regulation of protein localization to cell surface
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


627


12064


ENSG00000176697


ENSMUSG00000048482


P23560


P21237

RefSeq (mRNA)

NM_001143805 NM_001143806 NM_001143807 NM_001143808 NM_001143809
NM_001143810 NM_001143811 NM_001143812 NM_001143813 NM_001143814 NM_001143815 NM_001143816 NM_001709 NM_170731 NM_170732 NM_170733 NM_170734 NM_170735

NM_001048139 NM_001048141 NM_001048142 NM_007540 NM_001285416
NM_001285417 NM_001285418 NM_001285419 NM_001285420 NM_001285421 NM_001285422 NM_001316310

RefSeq (protein)

NP_001137277 NP_001137278 NP_001137279 NP_001137280 NP_001137281
NP_001137282 NP_001137283 NP_001137284 NP_001137285 NP_001137286 NP_001137288 NP_001700 NP_733927 NP_733928 NP_733929 NP_733930 NP_733931

NP_001041604.1 NP_001041606.1 NP_001041607.1 NP_001272345.1 NP_001272346.1
NP_001272347.1 NP_001272348.1 NP_001272349.1 NP_001272350.1 NP_001272351.1 NP_001303239.1 NP_001041604 NP_001041606 NP_001041607 NP_001272345 NP_001272346 NP_001272347 NP_001272348 NP_001272349 NP_001272350 NP_001272351 NP_001303239 NP_031566

Location (UCSC)

PubMed search