Big Spring Creek is a 5.0-mile-long (8.0 km)tributary of Conodoguinet Creek in Cumberland County, Pennsylvania in the United States.
Big Spring Creek, the fifth largest spring in Pennsylvania with a median flow of 18 million US gallons/27 cfs (0.7 m³/s) a day, emerges near U.S. Route 11, approximately 8 miles (13 km) northeast of Shippensburg, and feeds Conodoguinet Creek near Newville.
Note: Big Spring Creek is in the Lower Susquehanna River subbasin, but is not included above because its watershed area is less than 100 km².
Coordinates: 40°11′20″N 77°23′31″W / 40.1888°N 77.3919°W