Benzamidine

Benzamidine

Names
IUPAC name Benzenecarboximidamide
Identifiers
CAS Number	618-39-3 Y
3D model (Jmol)	Interactive image
ChEBI	CHEBI:41033 Y
ChemSpider	2242 Y
ECHA InfoCard	100.009.589
IUPHAR/BPS	7566
KEGG	C01784 Y
PubChem CID	2332
InChI InChI=1S/C7H8N2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H3,8,9) Y Key: PXXJHWLDUBFPOL-UHFFFAOYSA-N Y InChI=1/C7H8N2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H3,8,9) Key: PXXJHWLDUBFPOL-UHFFFAOYAU
SMILES [NH]=C(N)c1ccccc1
Properties
Chemical formula	C7H8N2
Molar mass	120.15 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y  (what is YN ?)
Infobox references

Benzamidine is a reversible competitive inhibitor of trypsin, trypsin-like enzymes and serine proteases.

It is often used as a ligand in protein crystallography to prevent proteases from degrading a protein of interest; the triangular diamine group at the bottom gives it a very obvious 'stick-man' shape which shows up in difference density maps. The benzamidine moiety is also found in some pharmaceuticals, like dabigatran.