Benperidol

Benperidol

Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	N05AD07 (WHO)
Legal status
Legal status	US: ℞-only
Identifiers
IUPAC name 1-{1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one
CAS Number	983-42-6 N
PubChem CID	16363
ChemSpider	15521 Y
UNII	97O6X78C53
ChEMBL	CHEMBL297302 Y
ECHA InfoCard	100.016.521
Chemical and physical data
Formula	C22H24FN3O2
Molar mass	381.443 g/mol
3D model (Jmol)	Interactive image
SMILES Fc1ccc(cc1)C(=O)CCCN4CCC(N3c2ccccc2NC3=O)CC4
InChI InChI=1S/C22H24FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-10,18H,3,6,11-15H2,(H,24,28) Y Key:FEBOTPHFXYHVPL-UHFFFAOYSA-N Y
NY (what is this?)

Benperidol is a drug which is a highly potent butyrophenone derivative. It is the most potent neuroleptic on the European market, with chlorpromazine equivalency as high as 75 to 100 (about 150 to 200% potency in terms of dose compared to haloperidol). It is an antipsychotic, which can be used for the treatment of schizophrenia, but it is primarily used to control antisocial hypersexual behaviour, and is sometimes prescribed to sex offenders as a condition of their parole, as an alternative to anti-androgen drugs such as cyproterone acetate.

Benperidol was discovered at Janssen Pharmaceutica in 1961.