BTN2A2

BTN2A2
Identifiers
Aliases	BTN2A2, BT2.2, BTF2, BTN2.2, Butyrophilin, subfamily 2, member A2, butyrophilin subfamily 2 member A2
External IDs	MGI: 3606486 HomoloGene: 56012 GeneCards: BTN2A2
Gene location (Human) Chr. Chromosome 6 (human) Band 6p22.2 Start 26,383,096 bp End 26,394,874 bp
Gene location (Mouse) Chr. Chromosome 13 (mouse) Band 13|13 A3.1 Start 23,477,676 bp End 23,488,857 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • protein binding Cellular component • integral component of membrane • extracellular exosome • membrane • plasma membrane Biological process • negative regulation of activated T cell proliferation • negative regulation of cytokine secretion • negative regulation of cellular metabolic process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	10385	238555
Ensembl	ENSG00000124508	ENSMUSG00000053216
UniProt	Q8WVV5	A4QPC6
RefSeq (mRNA)	NM_001197237 NM_001197238 NM_001197239 NM_001197240 NM_006995 NM_181531	NM_001289614 NM_001289615 NM_175938
RefSeq (protein)	NP_001184166 NP_001184167 NP_001184168 NP_001184169 NP_008926 NP_853509 NP_001184166.1 NP_008926.2	NP_001276543 NP_001276544 NP_787952
Location (UCSC)	Chr 6: 26.38 – 26.39 Mb	Chr 6: 23.48 – 23.49 Mb
PubMed search

10385

238555

ENSG00000124508

ENSMUSG00000053216

Q8WVV5

A4QPC6

NM_181531

NM_001289614
NM_001289615
NM_175938

NP_853509
NP_001184166.1
NP_008926.2

NP_001276543
NP_001276544
NP_787952

Butyrophilin subfamily 2 member A2 is a protein that in humans is encoded by the BTN2A2 gene.

Butyrophilin is the major protein associated with fat droplets in the milk. This gene is a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is a type 1 receptor glycoprotein involved in lipid, fatty-acid and sterol metabolism. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.

...
Wikipedia