BTAF1

BTAF1
Identifiers
Aliases	BTAF1, MOT1, TAF(II)170, TAF172, TAFII170, B-TFIID TATA-box binding protein associated factor 1
External IDs	MGI: 2147538 HomoloGene: 31978 GeneCards: BTAF1
Gene ontology Molecular function • transcription factor activity, sequence-specific DNA binding • DNA binding • nucleotide binding • hydrolase activity • ATP binding • helicase activity • protein binding Cellular component • intracellular membrane-bounded organelle • nucleus • nucleoplasm Biological process • negative regulation of transcription, DNA-templated • negative regulation of chromatin binding Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9044	107182
Ensembl	ENSG00000095564	ENSMUSG00000040565
UniProt	O14981 Q2M1V9	E9QAE3
RefSeq (mRNA)	NM_003972	NM_001080706
RefSeq (protein)	NP_003963 NP_003963.1	NP_001074175
Location (UCSC)	Chr 10: 91.92 – 92.03 Mb	Chr 19: 36.93 – 37.01 Mb
PubMed search

9044

107182

ENSG00000095564

ENSMUSG00000040565

O14981
Q2M1V9

E9QAE3

NM_003972

NM_001080706

NP_003963
NP_003963.1

NP_001074175

TATA-binding protein-associated factor 172 is a protein that in humans is encoded by the BTAF1 gene.

Initiation of transcription by RNA polymerase II requires the assistance of TATA box-binding protein (TBP; MIM 600075) and TBP-associated factors, or TAFs (e.g., TAF2B; MIM 604912), in 2 distinct complexes, TFIID and B-TFIID. The TFIID complex is composed of TBP and more than 8 TAFs. However, the majority of TBP is present in the B-TFIID complex, which is composed of TBP and TAFII170, also called TAF172, and has DNA-dependent ATPase activity.[supplied by OMIM]

BTAF1 has been shown to interact with TATA binding protein.

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Wikipedia