BRCT domain
| BRCA1 C Terminus (BRCT) domain | |||||||||
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Structure of an XRCC1 BRCT domain.
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| Identifiers | |||||||||
| Symbol | BRCT | ||||||||
| Pfam | PF00533 | ||||||||
| InterPro | IPR001357 | ||||||||
| SCOP | 1cdz | ||||||||
| SUPERFAMILY | 1cdz | ||||||||
| CDD | cd00027 | ||||||||
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| Available protein structures: | |
|---|---|
| Pfam | structures |
| PDB | RCSB PDB; PDBe; PDBj |
| PDBsum | structure summary |
BRCA1 C Terminus (BRCT) domain is a family of evolutionarily related proteins.
The BRCT domain (after the C_terminal domain of a breast cancer susceptibility protein) is found predominantly in proteins involved in cell cycle checkpoint functions responsive to DNA damage, for example as found in the breast cancer DNA-repair protein BRCA1. The domain is an approximately 100 amino acid tandem repeat, which appears to act as a phospho-protein binding domain.
Human proteins containing this domain include:
This article incorporates text from the public domain Pfam and InterPro IPR001357
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