BCL6

BCL6

Protein BCL6 PDB 1r28.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1R28, 1R29, 1R2B, 2EN2, 2EOS, 2LCE, 2YRM, 3BIM, 3E4U, 3LBZ, 4CP3, 4U2M

Identifiers

BCL6, BCL5, BCL6A, LAZ3, ZBTB27, ZNF51, B-cell CLL/lymphoma 6

External IDs

MGI: 107187 HomoloGene: 7640 GeneCards: BCL6

Gene ontology
Molecular function	• sequence-specific DNA binding • DNA binding • RNA polymerase II regulatory region sequence-specific DNA binding • transcription factor activity, sequence-specific DNA binding • intronic transcription regulatory region sequence-specific DNA binding • chromatin binding • metal ion binding • protein binding • transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding • nucleic acid binding • chromatin DNA binding • identical protein binding
Cellular component	• replication fork • nucleus • nucleoplasm • Golgi apparatus
Biological process	• regulation of germinal center formation • positive regulation of histone deacetylation • negative regulation of T-helper 2 cell differentiation • protein localization • negative regulation of mast cell cytokine production • regulation of transcription, DNA-templated • immune system process • regulation of GTPase activity • regulation of transcription from RNA polymerase II promoter • negative regulation of cell differentiation • protein import into nucleus, translocation • germinal center formation • negative regulation of Rho protein signal transduction • negative regulation of isotype switching to IgE isotypes • negative regulation of apoptotic process • negative regulation of transcription from RNA polymerase II promoter • transcription, DNA-templated • type 2 immune response • cellular response to DNA damage stimulus • negative regulation of cell-matrix adhesion • regulation of cell proliferation • positive regulation of B cell proliferation • negative regulation of cell growth • Rho protein signal transduction • cell morphogenesis • spermatogenesis • regulation of memory T cell differentiation • positive regulation of neuron differentiation • regulation of inflammatory response • regulation of immune response • positive regulation of apoptotic process • negative regulation of type 2 immune response • negative regulation of B cell apoptotic process • positive regulation of cellular component movement • B cell differentiation • inflammatory response • negative regulation of transcription, DNA-templated • actin cytoskeleton organization • negative regulation of cell proliferation • negative regulation of Notch signaling pathway • erythrocyte development • negative regulation of cellular senescence • regulation of apoptotic process
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE BCL6 203140 at tn.png

PBB GE BCL6 215990 s at tn.png

More reference expression data

Orthologs

Species

Human

Mouse


604


12053


ENSG00000113916


ENSMUSG00000022508


P41182


P41183

RefSeq (mRNA)


NM_001130845 NM_001134738 NM_001706 NM_138931


NM_009744 NM_001348026

RefSeq (protein)


NP_001124317 NP_001128210 NP_001697


NP_033874.1 NP_001334955 NP_033874

Location (UCSC)

Chr 3: 187.72 – 187.75 Mb

Chr 16: 23.97 – 23.99 Mb

PubMed search

1R28, 1R29, 1R2B, 2EN2, 2EOS, 2LCE, 2YRM, 3BIM, 3E4U, 3LBZ, 4CP3, 4U2M

ENSG00000113916

ENSMUSG00000022508

NM_001130845
NM_001134738
NM_001706
NM_138931

NM_009744
NM_001348026

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Wikipedia

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