BCL2L11

BCL2L11
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1F95, 2K7W, 2NL9, 2V6Q, 2VM6, 2WH6, 2YQ6, 2YQ7, 3D7V, 3FDL, 3IO8, 3IO9, 3KJ0, 3KJ1, 3KJ2, 4A1U, 4A1W, 4B4S, 4D2M, 4QVF, 4UF3, 4YJ4, 4ZIF, 4ZIH, 5AGW, 5AGX, 5C3G
Identifiers
Aliases	BCL2L11, BAM, BIM, BOD, BCL2 like 11
External IDs	MGI: 1197519 HomoloGene: 7643 GeneCards: BCL2L11
Gene ontology Molecular function • protein binding • microtubule binding • dynein complex binding Cellular component • cytoplasm • cytosol • membrane • intracellular membrane-bounded organelle • BIM-BCL-2 complex • mitochondrial outer membrane • BIM-BCL-xl complex • cytoplasmic dynein complex • mitochondrion • microtubule • endomembrane system • extrinsic component of membrane Biological process • leukocyte homeostasis • regulation of apoptotic process • positive regulation of protein homooligomerization • cellular process regulating host cell cycle in response to virus • male gonad development • positive regulation of cell death • positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway • B cell apoptotic process • kidney development • thymus development • lymphocyte homeostasis • positive regulation of apoptotic process by virus • myeloid cell homeostasis • post-embryonic animal organ morphogenesis • ear development • in utero embryonic development • B cell homeostasis • spleen development • thymocyte apoptotic process • post-embryonic development • response to endoplasmic reticulum stress • mammary gland development • T cell homeostasis • odontogenesis of dentin-containing tooth • positive regulation of IRE1-mediated unfolded protein response • positive regulation of cysteine-type endopeptidase activity involved in apoptotic process • tube formation • brain development • positive regulation of neuron apoptotic process • positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway • positive regulation of cell cycle • positive regulation of mitochondrial membrane permeability involved in apoptotic process • meiosis I • spermatogenesis • intrinsic apoptotic signaling pathway in response to DNA damage • extrinsic apoptotic signaling pathway in absence of ligand • positive regulation of apoptotic process • positive regulation of fibroblast apoptotic process • developmental pigmentation • positive regulation of release of cytochrome c from mitochondria • regulation of developmental pigmentation • cell-matrix adhesion • regulation of organ growth • activation of cysteine-type endopeptidase activity involved in apoptotic process • positive regulation of intrinsic apoptotic signaling pathway • apoptotic process involved in embryonic digit morphogenesis • apoptotic process • protein insertion into mitochondrial membrane involved in apoptotic signaling pathway Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	10018	12125
Ensembl	ENSG00000153094	ENSMUSG00000027381
UniProt	O43521	O54918
RefSeq (mRNA)	NM_001204106 NM_001204107 NM_001204108 NM_001204109 NM_001204110 NM_001204111 NM_001204112 NM_001204113 NM_006538 NM_138621 NM_138622 NM_138623 NM_138624 NM_138625 NM_138626 NM_138627 NM_207002 NM_207003	NM_001284410 NM_001291016 NM_009754 NM_207680 NM_207681
RefSeq (protein)	NP_001191035 NP_001191036 NP_001191037 NP_001191038 NP_001191039 NP_001191040 NP_001191041 NP_001191042 NP_006529 NP_619527 NP_619528 NP_619529 NP_619530 NP_619531 NP_619532 NP_619533 NP_996885 NP_996886	NP_033884.1 NP_997563.1 NP_997564.1 NP_001271339 NP_001277945 NP_033884 NP_997563 NP_997564
Location (UCSC)	Chr 2: 111.12 – 111.17 Mb	Chr 2: 128.13 – 128.16 Mb
PubMed search

1F95, 2K7W, 2NL9, 2V6Q, 2VM6, 2WH6, 2YQ6, 2YQ7, 3D7V, 3FDL, 3IO8, 3IO9, 3KJ0, 3KJ1, 3KJ2, 4A1U, 4A1W, 4B4S, 4D2M, 4QVF, 4UF3, 4YJ4, 4ZIF, 4ZIH, 5AGW, 5AGX, 5C3G

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