Autotaxin

ENPP2

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
4ZGA, 4ZG6, 4ZG9, 4ZG7

Identifiers

ENPP2, ATX, ATX-X, AUTOTAXIN, LysoPLD, NPP2, PD-IALPHA, PDNP2, ectonucleotide pyrophosphatase/phosphodiesterase 2

External IDs

Gene ontology
Molecular function	• nucleotide diphosphatase activity • phosphodiesterase I activity • transcription factor binding • polysaccharide binding • metal ion binding • scavenger receptor activity • catalytic activity • alkylglycerophosphoethanolamine phosphodiesterase activity • nucleic acid binding • hydrolase activity • calcium ion binding • lysophospholipase activity • zinc ion binding
Cellular component	• plasma membrane • integral component of plasma membrane • extracellular region • extracellular space
Biological process	• G-protein coupled receptor signaling pathway • regulation of cell migration • positive regulation of lamellipodium morphogenesis • lipid metabolic process • positive regulation of epithelial cell migration • regulation of angiogenesis • receptor-mediated endocytosis • lipid catabolic process • immune response • phospholipid catabolic process • positive regulation of peptidyl-tyrosine phosphorylation • phosphate-containing compound metabolic process • metabolic process • chemotaxis • phosphatidylcholine catabolic process • nucleic acid phosphodiester bond hydrolysis • cell motility
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


5168


18606


ENSG00000136960


ENSMUSG00000022425


Q13822


Q9R1E6

RefSeq (mRNA)


NM_001040092 NM_001130863 NM_006209 NM_001330600


NM_001136077 NM_015744 NM_001285994 NM_001285995

RefSeq (protein)


NP_001035181 NP_001124335 NP_001317529 NP_006200

NP_001129549.1 NP_001272923.1 NP_001272924.1 NP_056559.2 NP_001129549
NP_001272923 NP_001272924 NP_056559

Location (UCSC)

PubMed search