Augmentin
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| Combination of | |
|---|---|
| Amoxicillin | Penicillin antibiotic |
| Clavulanic acid | Beta-lactamase inhibitor |
| Clinical data | |
| Trade names | Augmentin, Clavulin, other |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a685024 |
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| Routes of administration |
by mouth, intravenous |
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Amoxicillin/clavulanic acid, also known as co-amoxiclav, is an antibiotic useful for the treatment of a number of bacterial infections. It is a combination consisting of amoxicillin, a β-lactam antibiotic, and potassium clavulanate, a β-lactamase inhibitor. It is specifically used for otitis media, strep throat, pneumonia, cellulitis, urinary tract infections, animal bites, and tuberculosis. It is taken by mouth or by injection into a vein.
Common side effects include diarrhea, vomiting, and allergic reactions. It also increases the risk of yeast infections, headaches, and blood clotting problems. It is not recommended in people with a history of a penicillin allergy. It is relatively safe for use during pregnancy.
Amoxicillin/clavulanic acid was approved for medical use in the United States in 1984. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. It is available as a generic medication. The wholesale cost in the developing world is about 0.18 to 1.14 USD per day. In the United States a course of treatment costs 50 to 100 USD.
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