Aryl hydrocarbon receptor nuclear translocator

ARNT

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
4PKY, 1X0O, 2A24, 2B02, 2HV1, 2K7S, 3F1N, 3F1O, 3F1P, 3H7W, 3H82, 4EQ1, 4GHI, 4GS9, 4H6J, 4LPZ, 4XT2

Identifiers

Aliases

ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2, aryl hydrocarbon receptor nuclear translocator

External IDs

OMIM: 126110 MGI: 88071 HomoloGene: 1261 GeneCards: ARNT

Gene ontology
Molecular function	• sequence-specific DNA binding • DNA binding • protein dimerization activity • transcription factor activity, transcription factor binding • transcription factor activity, sequence-specific DNA binding • aryl hydrocarbon receptor activity • transcription coactivator activity • aryl hydrocarbon receptor binding • transcription factor binding • enhancer binding • protein binding • protein heterodimerization activity • transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
Cellular component	• cytoplasm • transcription factor complex • nucleoplasm • RNA polymerase II transcription factor complex • nucleus • nuclear body
Biological process	• positive regulation of vascular endothelial growth factor receptor signaling pathway • cell differentiation • response to hypoxia • regulation of transcription, DNA-templated • positive regulation of endothelial cell proliferation • regulation of transcription from RNA polymerase II promoter in response to oxidative stress • positive regulation of erythrocyte differentiation • embryonic placenta development • mRNA transcription from RNA polymerase II promoter • positive regulation of protein sumoylation • transcription, DNA-templated • positive regulation of transcription, DNA-templated • intracellular receptor signaling pathway • regulation of transcription from RNA polymerase II promoter in response to hypoxia • positive regulation of vascular endothelial growth factor production • positive regulation of glycolytic process • positive regulation of transcription from RNA polymerase II promoter • positive regulation of hormone biosynthetic process • xenobiotic metabolic process
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


405


11863

Ensembl


ENSG00000143437


ENSMUSG00000015522

UniProt


P27540


P53762

RefSeq (mRNA)

NM_001197325 NM_001286035 NM_001286036 NM_001668 NM_178426
NM_178427 NM_001350224 NM_001350225 NM_001350226


NM_001037737 NM_009709

RefSeq (protein)

NP_001184254 NP_001272964 NP_001272965 NP_001659 NP_848514
NP_001337153 NP_001337154 NP_001337155


NP_001032826.1 NP_001032826 NP_033839

Location (UCSC)

Chr 1: 150.81 – 150.88 Mb

Chr 3: 95.43 – 95.5 Mb

PubMed search

4PKY, 1X0O, 2A24, 2B02, 2HV1, 2K7S, 3F1N, 3F1O, 3F1P, 3H7W, 3H82, 4EQ1, 4GHI, 4GS9, 4H6J, 4LPZ, 4XT2

NM_178427
NM_001350224
NM_001350225
NM_001350226

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