Dr. Arthur Lee (20 December 1740 – 12 December 1792) was a physician and opponent of slavery in colonial Virginia in North America who served as an American diplomat during the American Revolutionary War. He was educated in medicine and law at the University of Edinburgh and in London, respectively. After passing the bar, he practiced law in London for several years. He stayed in London during the Revolutionary War, representing the colonies to Britain and France and also serving as an American spy to track their activities. After his return to Virginia, he served as a delegate to the Continental Congress.
Born in Virginia, Arthur Lee was the youngest son of Hon. Thomas Lee (1690–1750) and Hannah Harrison Ludwell (1701–1750). Three of his five surviving elder brothers, Richard Henry Lee (1732–1794), Francis Lightfoot Lee (1734–1797) and William Lee (1739–1795), also became Revolutionary-era diplomats.
He attended Eton College in England and studied medicine at the University of Edinburgh, where he graduated in 1764. The title description of his thesis is: Dissertatio medica inauguralis, de cortice peruviano: quam ... ex auctoritate ... Gulielmi Robertson ... Academiae Edinburgenae praefecti ... pro gradu doctoratus ... eruditorum examini subjicit, Arthur Lee, Virginiensis. Ad diem septembris [1764] ... - Edinburgi : in aedibus A. Donaldson et J. Reid, MDCCLXIV. - 2 p. l., 47 p. ; 20 cm. In May, 13th 1765 he matriculated at the University of Leiden in the Netherlands.
During the latter period, Lee wrote in 1764, "An Essay in Vindication of the Continental Colonies of America," one of his more noted works. He opposed the Townshend acts and became a major proponent of American resistance to the British.