Aquaporin 9

AQP9
Identifiers
Aliases	AQP9, AQP-9, HsT17287, SSC1, T17287, aquaporin 9
External IDs	MGI: 1891066 HomoloGene: 41405 GeneCards: AQP9
Gene location (Human) Chr. Chromosome 15 (human) Band No data available Start 58,138,169 bp End 58,185,911 bp
Gene location (Mouse) Chr. Chromosome 9 (mouse) Band No data available Start 71,110,659 bp End 71,168,682 bp
Gene ontology Molecular function • porin activity • carboxylic acid transmembrane transporter activity • polyol transmembrane transporter activity • transporter activity • water transmembrane transporter activity • purine nucleobase transmembrane transporter activity • pyrimidine nucleobase transmembrane transporter activity • amine transmembrane transporter activity • water channel activity • urea channel activity • glycerol channel activity Cellular component • integral component of membrane • intracellular membrane-bounded organelle • membrane • plasma membrane • integral component of plasma membrane • basolateral plasma membrane Biological process • canalicular bile acid transport • excretion • water transport • amine transport • response to organic substance • water homeostasis • response to osmotic stress • polyol transport • carboxylic acid transport • immune response • pyrimidine nucleobase transport • response to mercury ion • metabolic process • glycerol transport • cellular response to cAMP • purine nucleobase transport • carboxylic acid transmembrane transport • purine nucleobase transmembrane transport • pyrimidine-containing compound transmembrane transport • transmembrane transport • urea transmembrane transport • transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	366	64008
Ensembl	ENSG00000103569	ENSMUSG00000032204
UniProt	O43315	Q9JJJ3
RefSeq (mRNA)	NM_020980 NM_001320635 NM_001320636	NM_001271843 NM_022026
RefSeq (protein)	NP_001307564 NP_001307565 NP_066190	NP_001258772 NP_071309
Location (UCSC)	Chr 15: 58.14 – 58.19 Mb	Chr 15: 71.11 – 71.17 Mb
PubMed search

366

64008

ENSG00000103569

ENSMUSG00000032204

O43315

Q9JJJ3

NM_020980
NM_001320635
NM_001320636

NM_001271843
NM_022026

NP_001307564
NP_001307565
NP_066190

NP_001258772
NP_071309

Aquaporin-9 is a protein that in humans is encoded by the AQP9 gene.

The aquaporins/major intrinsic protein are a family of water-selective membrane channels. Aquaporin 9 has greater sequence similarity with AQP3 and AQP7 and they may be a subfamily. Aquaporin 9 allows passage of a wide variety of noncharged solutes. AQP9 stimulates urea transport and osmotic water permeability; there are contradicting reports about its role in providing glycerol permeability. Aquaporin 9 may also have some role in specialized leukocyte functions such as immunological response and bactericidal activity.

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Wikipedia