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Angiotensin I

AGT
Angiotensins I and II comparison.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases AGT, ANHU, SERPINA8, angiotensinogen
External IDs MGI: 87963 HomoloGene: 14 GeneCards: AGT
RNA expression pattern
PBB GE AGT 202834 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000029

NM_007428

RefSeq (protein)

NP_000020

n/a

Location (UCSC) Chr 1: 230.7 – 230.71 Mb Chr 8: 124.56 – 124.57 Mb
PubMed search

4FYS, 1N9U, 1N9V, 2JP8, 2WXW, 2X0B, 3CK0, 3WOO, 3WOR, 4AA1, 4APH, 5E2Q

NM_000029

NM_007428

NP_000020

n/a

Angiotensin is a peptide hormone that causes vasoconstriction and a subsequent increase in blood pressure. It is part of the renin-angiotensin system, which is a major target for drugs that lower blood pressure. Angiotensin also stimulates the release of aldosterone, another hormone, from the adrenal cortex. Aldosterone promotes sodium retention in the distal nephron, in the kidney, which also drives blood pressure up.


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Wikipedia

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