Alfred Gilman, Sr.
| Alfred Gilman | |
|---|---|
 |
|
| Born |
February 5, 1908 Bridgeport, Connecticut |
| Died | January 13, 1984 (aged 75) New Haven, Connecticut |
| Fields | Pharmacology |
| Institutions |
Yale School of Medicine Columbia College of Physicians and Surgeons Albert Einstein College of Medicine |
| Alma mater | Yale University (B.S., Ph.D.) |
| Thesis | Chemical and Physiological Investigations on Canine Gastric Secretion (1934) |
| Academic advisors | George R. Cowgill |
| Known for | Experimental chemotherapy; The Pharmacological Basis of Therapeutics |
| Notable awards | National Academy of Sciences (1964) |
| Spouse | Mabel Schmidt |
| Children | Joanna Gilman Alfred G. Gilman |
Alfred Zack Gilman (February 5, 1908 – January 13, 1984) was an American pharmacologist best known for pioneering early chemotherapy techniques using nitrogen mustard with his colleague, Louis S. Goodman. The pair also published the classic textbook The Pharmacological Basis of Therapeutics in 1941, and Gilman served as an editor for its first six editions. Gilman served on the faculties of the Yale School of Medicine, the Columbia College of Physicians and Surgeons, and the Albert Einstein College of Medicine, where he founded the Department of Pharmacology. He was a member of U.S. National Academy of Sciences.
Gilman was born February 5, 1908 in Bridgeport, Connecticut, to Joseph Gilman and Rebecca Ives Gilman. Joseph Gilman owned a music store in Bridgeport, and his son learned to play several musical instruments. Unlike his father, however, Alfred Gilman turned to science, receiving a bachelor's degree from Yale College in 1928 and Ph.D. in Physiological Chemistry from Yale in 1931 for a dissertation entitled "Chemical and Physiological Investigations on Canine Gastric Secretion." He then joined of the Department of Pharmacology at the Yale School of Medicine as a postdoctoral fellow, where he and Louis S. Goodman, a young M.D., became colleagues and close friends. In 1934, a year before joining the Yale faculty as an assistant professor, he married Mabel Schmidt. Their daughter, Joanna, was born in 1938, and their son, Alfred Goodman Gilman, in 1941. The younger Alfred Gilman, whose middle name was taken from Louis Goodman, followed his father into pharmacology and was awarded the 1994 Nobel Prize in Medicine and Physiology.
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