Alfred G. Gilman
| Alfred G. Gilman | |
|---|---|
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| Born | Alfred Goodman Gilman July 1, 1941 New Haven, Connecticut |
| Died | December 23, 2015 (aged 74) Dallas, Texas, U.S. |
| Nationality | American |
| Fields |
Biochemistry Pharmacology |
| Alma mater |
Yale University (B.S., 1962) Case Western Reserve University (MD-Ph.D., 1969) |
| Known for | G proteins |
| Notable awards | John J. Abel Award (1975) Richard Lounsbery Award (1987) Louisa Gross Horwitz Prize (1989) Nobel Prize in Physiology or Medicine (1994) |
| Spouse | Kathryn Hedlund |
| Children | 3 |
Alfred Goodman Gilman (July 1, 1941 – December 23, 2015) was an American pharmacologist and biochemist. He and Martin Rodbell shared the 1994 Nobel Prize in Physiology or Medicine "for their discovery of G-proteins and the role of these proteins in signal transduction in cells."
Gilman was the son of Alfred Gilman, who co-authored Goodman & Gilman's The Pharmacological Basis of Therapeutics with Louis S. Goodman, from whom his middle name came. He earned a BA in biology with major in biochemistry from Yale University. Immediately after graduation in 1962, he worked with Allan Conney at Burroughs Wellcome & Company, which resulted in the publication of his first two technical papers. Persuaded by Earl Wilbur Sutherland, Jr., he joined Case Western Reserve University School of Medicine for an MD-PhD course. He obtained his degree in 1969. He then went to the National Institutes of Health to work with Marshall Nirenberg between 1969 and 1971.
Gilman became Assistant Professor of pharmacology at the University of Virginia School of Medicine in 1971, and full professor in 1977. He chaired the Department of Pharmacology at the University of Texas Southwestern Medical Center at Dallas from 1981. Upon his retirement in 2009, he was appointed chief scientific officer of the Cancer Prevention and Research Institute of Texas. He resigned in 2012. He was the founder of Regeneron company and the Alliance for Cellular Signaling. From 2005, he was also Director of Eli Lilly and Company.
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