Alfred Louis Olivier Legrand Des Cloizeaux (17 October 1817 – 6 May 1897) was a French mineralogist.
Des Cloizeaux was born at Beauvais, in the department of Oise. He studied with Jean-Baptiste Biot at the Collège de France. He became professor of mineralogy at the École Normale Supérieure and afterwards at the Muséum National d'Histoire Naturelle in Paris. He studied the geysers of Iceland, and wrote also on the classification of some of the eruptive rocks.
His main work consisted in the systematic examination of the crystals of numerous minerals, in researches on their optical properties and on the subject of light polarization. He demonstrated the circular polarization of cinnabar.
He wrote especially on the means of determining the different feldspars, and is credited with the discovery of microcline (a triclinic potash-feldspar). He named the minerals montebrasite (1871), binnite (a variety of tennantite) and Christianite (in honor of Christian VIII of Denmark). In 1854, Alexis Damour dedicated the mineral descloizite in honor of Des Cloizeaux.