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Alberto Mantovani (physician)

Alberto Mantovani
Alberto Mantovani medico.jpg
Born (1948-10-29) October 29, 1948 (age 68)
Milan, Italy
Residence Italy
Citizenship Italian
Fields Immunology
Institutions University of Milan
Humanitas University
University of Brescia
Mario Negri Institute for Pharmacological Research
Alma mater University of Milan
Known for Tumor-associated macrophages
Decoy receptor
CCL2
PTX3
Notable awards Robert Koch Prize, see text for others
Website
Page at Humanitas

Alberto Mantovani Commendatore OMRI (born 29 October 1948) is an Italian physician and immunologist. He is Scientific Director of Istituto Clinico Humanitas (Humanitas Clinical and Research Center), President and Founder of the Fondazione Humanitas per la Ricerca, and Professor of Pathology at the State University of Milan. He is known for his works in the roles of the immune system in the development of cancer. His research on tumor-associated macrophages (TAM, an acronym he coined) established inflammation as one of the causes of cancer. He was the first to identify monocyte chemotactic protein - 1 / CCL2 in 1983, and PTX3 in 1997. His works revealed the existence of decoy receptors in cell-signalling. He has been the most cited scientist in Italy, and one of the ten most cited immunologists worldwide.

Mantovani was born in Milan on 29 October 1948. He studied medicine at the University of Milan and graduated (summa cum laude) in 1973. In 1976 he earned a specialization in oncology at the University of Pavia. Between 1973 and 1976, he worked as a visiting fellow at the Department of Tumor Immunology of the Chester Beatty Research Institute (now the Institute of Cancer Research) in Belmont, Sutton, England, where he continued the studies of Iwan Robert Evans and Peter Alexander. Between 1978 and 1979 he was a visiting fellow at the Laboratory of Immunodiagnosis at the National Institutes of Health in Bethesda, Maryland. In 1979 he was appointed Senior investigator in the Department of Tumor Immunology and Chemotherapy at the Istituto di Ricerche Farmacologiche "Mario Negri" in Milan. He became the Chief of Laboratory of the institute in 1981. In 1987 he worked at the Laboratory of Molecular Immunoregulation of NIH in Frederick, Maryland, as an Eleanor Roosvelt UICC Scholar. In 1994 he was promoted to Full Professor of General Pathology in the School of Medicine at the University of Brescia. He became Head of the Department of Immunology and Cell Biology at Istituto di Ricerche Farmacologiche "Mario Negri" in 1996. Between 2001 and 2014, he also served as Full Professor of General Pathology in the School of Medicine of the State University of Milan. Then he continued as Full Professor of General Pathology at Humanitas University in 2014. In 2005 he became the Scientific Director of Istituto Clinico Humanitas and President of Fondazione Humanitas per la Ricerca (under Humanitas University).


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