alanine dehydrogenase | |||||||||
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Identifiers | |||||||||
EC number | 1.4.1.1 | ||||||||
CAS number | 9029-06-5 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Search | |
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PMC | articles |
PubMed | articles |
NCBI | proteins |
Alanine dehydrogenase (EC 1.4.1.1) is an enzyme that catalyzes the chemical reaction
The 3 substrates of this enzyme are L-alanine, water, and nicotinamide adenine dinucleotide+, whereas its 4 products are pyruvate, ammonia, NADH, and hydrogen ion.
his enzyme participates in taurine and hypotaurine metabolism and reductive carboxylate cycle (CO2 fixation).
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-alanine:NAD+ oxidoreductase (deaminating). Other names in common use include AlaDH, L-alanine dehydrogenase, NAD+-linked alanine dehydrogenase, alpha-alanine dehydrogenase, NAD+-dependent alanine dehydrogenase, alanine oxidoreductase, and NADH-dependent alanine dehydrogenase. T
Alanine dehydrogenase contains both a N-terminus and C-terminus domains.