Air Sénégal International was an airline with its head office in Dakar, Senegal. It was a regional carrier operating a scheduled domestic network and regional flights to neighbouring countries. It also operated charter and air taxi flights. Its main base was Dakar-Yoff-Léopold Sédar Senghor International Airport.

On April 24, 2009, the airline suspended all of its operations.

The airline was established on 1 February 1971 as Air Sénégal and started operations on 23 February 2001. It was restructured as an international carrier following the acquisition of a majority stake by Royal Air Maroc in 2001. It was part of Groupe Royal Air Maroc, who owned 51% of the company's shares, with 49% being held by the Senegalese government.

At one time the airline had its head office on the grounds of Dakar-Yoff-Léopold Sédar Senghor International Airport in Yoff, Senegal.

In 2006 the airline disclosed losses of $16 million. In 2007, the Senegalese government stated that effective 5 November 2006, it would purchase a further 26% of the airline, raising its stake to 75%. The Senegalese government stated that support from Royal Air Maroc had "shown its limitations", and that the airline needed to be recapitalised.

In late 2009, a new airline was announced to replace Air Sénégal International. The new airline is called Senegal Airlines with a fleet of 4 Airbus A320 aircraft and 2 Airbus A330 aircraft. Operations commenced in early 2011.

As of 2007, Air Sénégal International operated scheduled passenger flights to the following destinations:

At May 2007, Air Sénégal International had codeshare agreements with the following airlines:

At March 2008, the Air Sénégal International fleet consisted of the following aircraft:

At August 2006 the airline also operated:

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