ATP7A

ATP7A
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1AW0, 1KVI, 1KVJ, 1Q8L, 1S6O, 1S6U, 1Y3J, 1Y3K, 1YJR, 1YJT, 1YJU, 1YJV, 2G9O, 2GA7, 2K1R, 2KIJ, 2KMV, 2KMX, 3CJK
Identifiers
Aliases	ATP7A, DSMAX, MK, MNK, SMAX3, ATPase copper transporting alpha
External IDs	OMIM: 300011 MGI: 99400 HomoloGene: 35 GeneCards: ATP7A
Gene ontology Molecular function • nucleotide binding • copper ion binding • metal ion binding • hydrolase activity • cation-transporting ATPase activity • copper ion transmembrane transporter activity • ATP binding • superoxide dismutase copper chaperone activity • copper-dependent protein binding • protein binding • Rac GTPase binding • chaperone binding • copper-exporting ATPase activity Cellular component • trans-Golgi network transport vesicle • cytoplasm • integral component of membrane • trans-Golgi network • Golgi apparatus • cytosol • neuron projection • membrane • neuronal cell body • endoplasmic reticulum • perinuclear region of cytoplasm • brush border membrane • basolateral plasma membrane • secretory granule • plasma membrane • nucleus • late endosome • microvillus • apical plasma membrane • phagocytic vesicle membrane • cell leading edge • perikaryon • membrane raft Biological process • norepinephrine metabolic process • response to iron(III) ion • removal of superoxide radicals • detoxification of copper ion • copper ion import • neuron projection morphogenesis • pyramidal neuron development • extracellular matrix organization • collagen fibril organization • dopamine metabolic process • T-helper cell differentiation • skin development • tryptophan metabolic process • response to zinc ion • regulation of oxidative phosphorylation • locomotory behavior • cartilage development • response to copper ion • positive regulation of oxidoreductase activity • pigmentation • serotonin metabolic process • ion transport • blood vessel development • mitochondrion organization • cerebellar Purkinje cell differentiation • transport • elastic fiber assembly • central nervous system neuron development • cation transport • in utero embryonic development • ion transmembrane transport • lung alveolus development • blood vessel remodeling • peptidyl-lysine modification • catecholamine metabolic process • metal ion transport • hair follicle morphogenesis • plasma membrane copper ion transport • lactation • positive regulation of catalytic activity • epinephrine metabolic process • elastin biosynthetic process • cellular copper ion homeostasis • copper ion transport • negative regulation of catalytic activity • liver development • response to manganese ion • response to lead ion • regulation of gene expression • positive regulation of lamellipodium assembly • antimicrobial humoral response • negative regulation of iron ion transmembrane transport • cellular response to platelet-derived growth factor stimulus • positive regulation of cell size • positive regulation of epithelial cell proliferation • cellular response to amino acid stimulus • cellular response to antibiotic • cellular response to cadmium ion • cellular response to cobalt ion • cellular response to copper ion • cellular response to iron ion • cellular response to lead ion • cellular response to hypoxia • ATP hydrolysis coupled cation transmembrane transport • positive regulation of response to wounding • positive regulation of vascular associated smooth muscle cell migration • regulation of cytochrome-c oxidase activity • copper ion export Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	538	11977
Ensembl	ENSG00000165240	ENSMUSG00000033792
UniProt	Q04656	Q64430
RefSeq (mRNA)	NM_000052 NM_001282224	NM_001109757 NM_009726
RefSeq (protein)	NP_000043 NP_001269153	NP_033856.3 NP_001103227 NP_033856
Location (UCSC)	Chr X: 77.91 – 78.05 Mb	Chr X: 106.03 – 106.12 Mb
PubMed search

1AW0, 1KVI, 1KVJ, 1Q8L, 1S6O, 1S6U, 1Y3J, 1Y3K, 1YJR, 1YJT, 1YJU, 1YJV, 2G9O, 2GA7, 2K1R, 2KIJ, 2KMV, 2KMX, 3CJK

538

11977

ENSG00000165240

ENSMUSG00000033792

Q04656

...
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