ATG5

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
4GDK, 4GDL, 4NAW, 4TQ0, 4TQ1, 5D7G

Identifiers

Aliases

ATG5, APG5, APG5-LIKE, APG5L, ASP, hAPG5, autophagy related 5

External IDs

MGI: 1277186 HomoloGene: 3566 GeneCards: ATG5

Gene ontology
Molecular function	• Atg8 ligase activity • protein binding
Cellular component	• cytoplasm • pre-autophagosomal structure membrane • cytosol • phagocytic vesicle membrane • membrane • Atg12-Atg5-Atg16 complex • autophagosome • axoneme • ER-mitochondrion membrane contact site
Biological process	• immune system process • negative regulation of cell death • autophagy • C-terminal protein lipidation • nucleophagy • cellular response to nitrogen starvation • apoptotic process • innate immune response • autophagosome assembly • mitophagy • blood vessel remodeling • regulation of cytokine secretion involved in immune response • cellular response to starvation • response to fungus • macroautophagy • cellular homeostasis • antigen processing and presentation of endogenous antigen • negative regulation of protein ubiquitination • aggrephagy • negative stranded viral RNA replication • vasodilation • response to drug • negative regulation of apoptotic process • post-translational protein modification • negative thymic T cell selection • otolith development • negative regulation of phagocytosis • regulation of release of sequestered calcium ion into cytosol • ventricular cardiac muscle cell development • heart contraction • protein lipidation involved in autophagosome assembly • positive regulation of mucus secretion • cellular response to nitrosative stress • regulation of cilium assembly • regulation of reactive oxygen species metabolic process • negative regulation of reactive oxygen species metabolic process • negative regulation of histone H4-K16 acetylation • autophagy of host cells involved in interaction with symbiont
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


9474


11793

Ensembl


ENSG00000057663


ENSMUSG00000038160

UniProt


Q9H1Y0


Q99J83

RefSeq (mRNA)


NM_001286106 NM_001286107 NM_001286108 NM_001286111 NM_004849


NM_053069 NM_001314013

RefSeq (protein)


NP_001273035 NP_001273036 NP_001273037 NP_001273040 NP_004840


NP_001300942.1 NP_444299.1 NP_001300942 NP_444299

Location (UCSC)

Chr 6: 106.18 – 106.33 Mb

Chr 10: 44.27 – 44.36 Mb

PubMed search

4GDK, 4GDL, 4NAW, 4TQ0, 4TQ1, 5D7G

NM_001286106
NM_001286107
NM_001286108
NM_001286111
NM_004849

NM_053069
NM_001314013

NP_001273035
NP_001273036
NP_001273037
NP_001273040
NP_004840

...
Wikipedia