ASH2L

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3RSN, 3S32, 3TOJ, 4RIQ, 4X8N, 4X8P, 5F6L, 5F6K

Identifiers

ASH2L, ASH2, ASH2L1, ASH2L2, Bre2, ASH2 like histone lysine methyltransferase complex subunit

External IDs

Gene ontology
Molecular function	• euchromatin binding • DNA binding • beta-catenin binding • histone methyltransferase activity (H3-K4 specific) • metal ion binding • protein binding • transcription regulatory region DNA binding • histone-lysine N-methyltransferase activity
Cellular component	• nuclear euchromatin • Set1C/COMPASS complex • nucleoplasm • MLL1 complex • MLL3/4 complex • nucleus • histone methyltransferase complex
Biological process	• hemopoiesis • regulation of transcription, DNA-templated • transcription from RNA polymerase II promoter • transcription, DNA-templated • cellular response to DNA damage stimulus • response to estrogen • histone H3-K4 methylation • positive regulation of cell proliferation • positive regulation of transcription from RNA polymerase II promoter • beta-catenin-TCF complex assembly • covalent chromatin modification
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


9070


23808


ENSG00000129691


ENSMUSG00000031575


Q9UBL3


Q91X20

RefSeq (mRNA)


NM_001105214 NM_001261832 NM_001282272 NM_004674


NM_001080793 NM_001286207 NM_011791

RefSeq (protein)


NP_001098684 NP_001248761 NP_001269201 NP_004665


NP_035921.2 NP_001074262 NP_001273136 NP_035921

Location (UCSC)

PubMed search