ARTS-1

ERAP1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2YD0, 3MDJ, 3QNF, 3RJO

Identifiers

Aliases

ERAP1, A-LAP, ALAP, APPILS, ARTS-1, ARTS1, ERAAP, ERAAP1, PILS-AP, PILSAP, endoplasmic reticulum aminopeptidase 1

External IDs

MGI: 1933403 HomoloGene: 56754 GeneCards: ERAP1

Genetically Related Diseases

ankylosing spondylitis

Gene ontology
Molecular function	• interleukin-6 receptor binding • peptide binding • zinc ion binding • metal ion binding • interleukin-1, Type II receptor binding • peptidase activity • protein binding • aminopeptidase activity • metalloexopeptidase activity • hydrolase activity • metallopeptidase activity • endopeptidase activity • metalloaminopeptidase activity
Cellular component	• cytoplasm • integral component of membrane • cytosol • endoplasmic reticulum membrane • membrane • extracellular region • endoplasmic reticulum • extracellular exosome • extracellular space • endoplasmic reticulum lumen
Biological process	• regulation of innate immune response • adaptive immune response • response to bacterium • immune system process • antigen processing and presentation of peptide antigen via MHC class I • proteolysis • positive regulation of angiogenesis • membrane protein ectodomain proteolysis • angiogenesis • fat cell differentiation • peptide catabolic process • antigen processing and presentation of endogenous peptide antigen via MHC class I • regulation of blood pressure • signal transduction • cell-cell signaling
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


51752


80898

Ensembl


ENSG00000164307


ENSMUSG00000021583

UniProt


Q9NZ08


Q9EQH2

RefSeq (mRNA)


NM_001040458 NM_001198541 NM_016442 NM_001349244


NM_030711

RefSeq (protein)


NP_001035548 NP_001185470 NP_057526 NP_001336173


NP_109636.1 NP_109636

Location (UCSC)

Chr 5: 96.76 – 96.81 Mb

Chr 13: 74.64 – 74.69 Mb

PubMed search

2YD0, 3MDJ, 3QNF, 3RJO

NM_001040458
NM_001198541
NM_016442
NM_001349244

NM_030711

NP_001035548
NP_001185470
NP_057526
NP_001336173

NP_109636.1
NP_109636

...
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