ARHGAP9

ARHGAP9
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 2P0D, 2P0H
Identifiers
Aliases	ARHGAP9, 10C, RGL1, Rho GTPase activating protein 9
External IDs	MGI: 2143764 HomoloGene: 13041 GeneCards: ARHGAP9
Gene ontology Molecular function • protein binding • phosphatidylinositol-3,4,5-trisphosphate binding • lipid binding • GTPase activator activity Cellular component • cytosol • extracellular region • secretory granule lumen Biological process • regulation of small GTPase mediated signal transduction • signal transduction • positive regulation of GTPase activity • neutrophil degranulation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	64333	216445
Ensembl	ENSG00000123329	ENSMUSG00000040345
UniProt	Q9BRR9	n/a
RefSeq (mRNA)	NM_001080156 NM_001080157 NM_032496 NM_001319850 NM_001319851 NM_001319852	NM_001285785 NM_146011
RefSeq (protein)	NP_001073625 NP_001073626 NP_001306779 NP_001306780 NP_001306781 NP_115885 NP_001306779.1	n/a
Location (UCSC)	Chr 12: 57.47 – 57.49 Mb	Chr 10: 127.32 – 127.33 Mb
PubMed search

2P0D, 2P0H

64333

216445

ENSG00000123329

ENSMUSG00000040345

Q9BRR9

n/a

NM_001319852

NM_001285785
NM_146011

NP_115885
NP_001306779.1

n/a

Rho GTPase-activating protein 9 is an enzyme that in humans is encoded by the ARHGAP9 gene.

This gene encodes a member of the Rho-GAP family of GTPase activating proteins. The protein has substantial GAP activity towards several Rho-family GTPases in vitro, converting them to an inactive GDP-bound state. It is implicated in regulating adhesion of hematopoietic cells to the extracellular matrix. Multiple transcript variants encoding different isoforms have been found for this gene.

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