ARG1

ARG1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1WVA, 1WVB, 2AEB, 2PHA, 2PHO, 2PLL, 2ZAV, 3DJ8, 3E6K, 3E6V, 3F80, 3GMZ, 3GN0, 3KV2, 3LP4, 3LP7, 3MFV, 3MFW, 3MJL, 3SJT, 3SKK, 3TF3, 3TH7, 3THE, 3THH, 3THJ, 4FCI, 4FCK, 4GSM, 4GSV, 4GSZ, 4GWC, 4GWD, 4HWW, 4HXQ, 4IE1
Identifiers
Aliases	ARG1, arginase 1
External IDs	MGI: 88070 HomoloGene: 29 GeneCards: ARG1
Gene ontology Molecular function • arginase activity • manganese ion binding • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines • metal ion binding • hydrolase activity Cellular component • cytoplasm • cytosol • mitochondrial outer membrane • neuronal cell body • neuron projection • extracellular exosome • nucleus • extracellular region • extracellular space • azurophil granule lumen • specific granule lumen Biological process • cellular response to interleukin-4 • cellular response to transforming growth factor beta stimulus • response to selenium ion • response to amino acid • response to cadmium ion • positive regulation of endothelial cell proliferation • maternal process involved in female pregnancy • lung development • urea cycle • female pregnancy • response to steroid hormone • cellular response to glucagon stimulus • aging • response to peptide hormone • response to zinc ion • arginine catabolic process • arginine metabolic process • response to vitamin E • protein homotrimerization • cellular response to dexamethasone stimulus • response to vitamin A • arginine catabolic process to ornithine • response to lipopolysaccharide • response to manganese ion • response to wounding • response to axon injury • collagen biosynthetic process • response to amine • liver development • response to methylmercury • cellular response to lipopolysaccharide • response to herbicide • response to drug • regulation of L-arginine import • cellular response to hydrogen peroxide • mammary gland involution • neutrophil degranulation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	383	11846
Ensembl	ENSG00000118520	ENSMUSG00000019987
UniProt	P05089	Q61176
RefSeq (mRNA)	NM_000045 NM_001244438	NM_007482
RefSeq (protein)	NP_000036 NP_001231367	NP_031508
Location (UCSC)	Chr 6: 131.57 – 131.58 Mb	Chr 10: 24.92 – 24.93 Mb
PubMed search

1WVA, 1WVB, 2AEB, 2PHA, 2PHO, 2PLL, 2ZAV, 3DJ8, 3E6K, 3E6V, 3F80, 3GMZ, 3GN0, 3KV2, 3LP4, 3LP7, 3MFV, 3MFW, 3MJL, 3SJT, 3SKK, 3TF3, 3TH7, 3THE, 3THH, 3THJ, 4FCI, 4FCK, 4GSM, 4GSV, 4GSZ, 4GWC, 4GWD, 4HWW, 4HXQ, 4IE1

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