APRIL (protein)

TNFSF13
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4ZCH
Identifiers
Aliases	TNFSF13, APRIL, CD256, TALL-2, TALL2, TRDL-1, ZTNF2, UNQ383/PRO715, TNLG7B, tumor necrosis factor superfamily member 13
External IDs	MGI: 1916833 HomoloGene: 56971 GeneCards: TNFSF13
Gene ontology Molecular function • receptor binding • tumor necrosis factor receptor binding • cytokine activity Cellular component • cytosol • membrane • nucleoplasm • cytoplasm • extracellular exosome • extracellular region • extracellular space Biological process • tumor necrosis factor-mediated signaling pathway • regulation of mRNA stability • positive regulation of cell proliferation • immune system process • signal transduction • positive regulation of isotype switching to IgA isotypes • immune response Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	8741	69583
Ensembl	ENSG00000161955	ENSMUSG00000089669
UniProt	O75888	Q9D777
RefSeq (mRNA)	NM_001198622 NM_001198623 NM_001198624 NM_003808 NM_172087 NM_172088	NM_001159505 NM_023517
RefSeq (protein)	NP_001185551 NP_001185552 NP_001185553 NP_003799 NP_742084 NP_742085	NP_001152977.1 NP_076006.2 NP_001152977 NP_076006
Location (UCSC)	Chr 17: 7.56 – 7.56 Mb	Chr 11: 69.68 – 69.69 Mb
PubMed search

4ZCH

8741

69583

ENSG00000161955

ENSMUSG00000089669

O75888

Q9D777

NM_172088

NM_001159505
NM_023517

NP_742085

NP_001152977.1
NP_076006.2
NP_001152977
NP_076006

A proliferation-inducing ligand (APRIL), also known as tumor necrosis factor ligand superfamily member 13 (TNFSF13), is a protein of the TNF superfamily recognized by the cell surface receptor TACI.

In the cluster of differentiation terminology, APRIL is designated CD256.

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