AMY1A

AMY1A
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 1C8Q, 1JXJ, 1JXK, 1MFU, 1MFV, 1NM9, 1Q4N, 1SMD, 1XV8, 1Z32, 3BLK, 3BLP, 3DHP
Identifiers
Aliases	AMY1A, AMY1, amylase, alpha 1A (salivary)
External IDs	HomoloGene: 133998 GeneCards: AMY1A
Gene ontology Molecular function • protein binding • alpha-amylase activity • hydrolase activity • catalytic activity • metal ion binding • hydrolase activity, acting on glycosyl bonds • cation binding Cellular component • extracellular region • extracellular exosome • extracellular space Biological process • digestion • metabolic process • carbohydrate metabolic process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	276	n/a
Ensembl	ENSG00000237763	n/a
UniProt	P04745	n/a
RefSeq (mRNA)	NM_004038 NM_001008221	n/a
RefSeq (protein)	NP_001008219	n/a
Location (UCSC)	Chr 1: 103.66 – 103.66 Mb	n/a
PubMed search		n/a

1C8Q, 1JXJ, 1JXK, 1MFU, 1MFV, 1NM9, 1Q4N, 1SMD, 1XV8, 1Z32, 3BLK, 3BLP, 3DHP

276

n/a

ENSG00000237763

n/a

P04745

n/a

NM_004038
NM_001008221

n/a

NP_001008219

n/a

Alpha-amylase 1 is an enzyme that in humans is encoded by the AMY1A gene. This gene is found in many organisms, see Alpha-Amylase.

Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the salivary gland. Alternative splicing results in multiple transcript variants encoding the same protein.

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