AKT2

AKT2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1GZK, 1GZN, 1GZO, 1MRV, 1MRY, 1O6K, 1O6L, 1P6S, 2JDO, 2JDR, 2UW9, 2X39, 2XH5, 3D0E, 3E87, 3E88, 3E8D
Identifiers
Aliases	AKT2, v-akt murine thymoma viral oncogene homolog 2, HIHGHH, PKBB, PKBBETA, PRKBB, RAC-BETA, AKT serine/threonine kinase 2
External IDs	MGI: 104874 HomoloGene: 48773 GeneCards: AKT2
Gene ontology Molecular function • transferase activity • nucleotide binding • protein kinase activity • kinase activity • protein serine/threonine kinase activity • protein binding • ATP binding Cellular component • cytoplasm • endosome • membrane • plasma membrane • nucleoplasm • ruffle membrane • cell cortex • early endosome • nucleus • cytosol Biological process • positive regulation of protein targeting to membrane • apoptotic process • positive regulation of fatty acid beta-oxidation • insulin receptor signaling pathway • positive regulation of protein phosphorylation • intracellular signal transduction • regulation of cell migration • peripheral nervous system myelin maintenance • positive regulation of glycogen biosynthetic process • positive regulation of cell motility • intracellular protein transmembrane transport • activation of GTPase activity • carbohydrate metabolic process • phosphorylation • positive regulation of glucose metabolic process • positive regulation of glucose import in response to insulin stimulus • mammary gland epithelial cell differentiation • multicellular organism development • protein phosphorylation • negative regulation of plasma membrane long-chain fatty acid transport • cellular protein modification process • glycogen biosynthetic process • positive regulation of vesicle fusion • peptidyl-serine phosphorylation • glucose metabolic process • cellular response to insulin stimulus • transport • glycogen metabolic process • protein localization to plasma membrane • regulation of translation • fat cell differentiation • regulation of cell cycle arrest • signal transduction • carbohydrate transport • positive regulation of cell migration • positive regulation of glucose import Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	208	11652
Ensembl	ENSG00000105221	ENSMUSG00000004056
UniProt	P31751	Q60823
RefSeq (mRNA)	NM_001243027 NM_001243028 NM_001626 NM_001330511	NM_001110208 NM_007434 NM_001331108 NM_001331109
RefSeq (protein)	NP_001229956 NP_001229957 NP_001317440 NP_001617	NP_001103678.1 NP_031460.1 NP_001103678 NP_001318037 NP_001318038 NP_031460
Location (UCSC)	Chr 19: 40.23 – 40.29 Mb	Chr 7: 27.59 – 27.64 Mb
PubMed search

1GZK, 1GZN, 1GZO, 1MRV, 1MRY, 1O6K, 1O6L, 1P6S, 2JDO, 2JDR, 2UW9, 2X39, 2XH5, 3D0E, 3E87, 3E88, 3E8D

208

11652

ENSG00000105221

ENSMUSG00000004056

P31751

Q60823

NM_001243027
NM_001243028
NM_001626
NM_001330511

...
Wikipedia